欧洲血脑屏障技术市场预测至 2028 年 - COVID-19 影响和技术区域分析(双特异性抗体 RMT 方法、特洛伊木马方法、增加渗透性、被动扩散和其他非侵入性 BBB 技术)和应用(阿尔茨海默氏症)疾病、癫痫、帕金森病、多发性硬化症、亨特综合症、脑癌等)

TIPRE00026226 | Pages: 132 | Biotechnology | Dec 2021 | Type: Regional | Status: Published

市场介绍

欧洲血脑屏障技术由德国、英国、法国、意大利、西班牙和欧洲其他国家。 2021年,德国占据了最大的市场份额。德国在医疗保健行业方面遥遥领先。它拥有来自世界各地的市场领导者。此外,全国各地都有知名企业为整个医疗保健行业做出贡献,包括神经系统疾病的诊断和治疗。血脑屏障技术行业在德国是一个利润丰厚的行业,这是由脑膜炎、多发性硬化症、帕金森病和脑炎等神经系统疾病日益流行等因素推动的。例如,根据 Globocan 的数据,2020 年脑部、中枢神经系统癌症新发病例数为 7697 例。同样,根据 NCBI 2017 年发布的数据,德国脑部相关动脉瘤的患病率约为每 10 万人中 11.3 例。 2011 年,患病率达到每 10 万人 22.1 人。此外,2013 年,患病率达到每 10 万人 22.1 人。脑动脉瘤患病率的增加预计将在 2020 年至 2027 年期间推动德国脑动脉瘤市场的发展。此外,根据欧洲阿尔茨海默病协会的数据,2019年,德国共有1,585,166名阿尔茨海默病患者,痴呆症患者总数将从2018年的1,585,166人增加到2050年的2,748,178人。同样,从占总人口的比例来看,到 2050 年,患有痴呆症的人将占 3.43%,而 2018 年为 1.91%。

由于该地区 COVID-19 病例呈指数级增长,欧洲经济受到严重影响。西班牙、意大利、德国、法国和英国是受影响最严重的欧洲国家。此外,新的证据支持了一年前的理论,即 Covid-19 感染会导致神经系统问题。这种观点最初是在去年夏天第一波疫情期间提出的。根据伦敦帝国理工学院四位学者的初步(尚未经过同行评审)研究,这一点现已得到充分证明。 Jiabin Tang、Shivani Patel、Steve Gentleman 和 Paul M Matthew 撰写了预印本,指出了病毒进入神经系统的“潜在途径”。血脑屏障是内皮细胞的半透膜,可保护大脑免受身体其他部位的影响。单核细胞是一种白细胞,当 SARS-CoV-2 进入血液时,它会被激活,作为人体防御机制的一部分。为了让单核细胞穿过血脑屏障,需要激活一个复杂的机制。文章称,“这有助于受感染和激活的单核细胞进入中枢神经系统,从而使 SARS-CoV-2 病毒能够通过松弛的血脑屏障。

市场概况和动态

欧洲血脑屏障技术市场预计将从 2019 年的 3.1997 亿美元增长2021 年到 2028 年将达到 15.4876 亿美元;预计 2021 年至 2028 年复合年增长率为 25.3%。纳米医学是一个快速发展的领域,将纳米颗粒或纳米结构用于医疗应用,特别是在向大脑输送药物的欠发达领域人们对多功能纳米颗粒(NP)穿越血脑屏障的能力寄予厚望。纳米技术的最新进展使得原本在大脑中分布不佳的药物能够被包装成具有脑靶向特性的纳米颗粒。这些靶向载体系统增强了通过将药物捕获或封装在颗粒中并在其表面上具有靶向肽/配体来递送药物,从而导致 BBB 靶向。这些载体系统利用跨细胞途径(例如受体介导的内吞作用)穿过血脑屏障。固体脂质纳米颗粒的一个显着优点是它们的高脂溶性可以物理稳定纳米颗粒,从而增加药物的承载能力并导致药物的受控释放速率。尽管基于脂质的纳米颗粒和制剂由于渗透和滞留增加而具有延长的体循环时间和增加的肿瘤滞留,但它们最重要的限制因素是通过网状内皮系统从血流中快速清除。一些研究小组正在努力通过安装带有配体的纳米颗粒来改善对大脑的靶向性,这些配体是 BBB 摄取转运蛋白的底物,有助于转运到大脑。随着这项技术的进步,该系统可以有效地输送多种具有良好毒性的治疗药物。因此,使用纳米粒子进行脑部药物输送预计将成为预测期内的趋势

关键细分市场

在技术方面,增加渗透性细分市场在2021年欧洲血脑屏障技术市场中占据最大份额。应用方面,帕金森氏病细分市场在 2021 年占据欧洲血脑屏障技术市场的最大份额。

主要来源和上市公司

准备本欧洲血脑屏障技术市场报告时提到的一些主要一手和二手来源包括公司网站、年报、财务报告、国家政府文件、统计数据库等。报告中列出的主要公司有梯瓦制药工业有限公司(Teva Pharmaceutical Industries Ltd.); F.霍夫曼-拉罗氏有限公司;礼来公司;百时美施贵宝公司;辉瑞公司;强生公司约翰逊服务公司;法布尔-克莱默制药公司;阿布利瓦公司;和 Bioasis Technologies, Inc. 等

购买报告的理由

  • 了解欧洲血脑屏障技术市场格局并确定最有可能保证丰厚回报
  • 了解欧洲血脑屏障技术市场不断变化的竞争格局,保持领先地位
  • 通过识别最有可能销售的细分市场,有效规划欧洲血脑屏障技术市场的并购和合作交易
  • 帮助通过敏锐和全面的分析做出明智的业务决策欧洲血脑屏障技术市场各个细分市场的市场表现
  • 获取欧洲地区2021-2028年各个细分市场的市场收入预测。 >

欧洲血脑屏障技术市场细分

欧洲血脑屏障技术市场 –按技术

  • 双特异性抗体RMT方法
  • 特洛伊木马方法
  • 增加渗透性
  • 被动扩散
  • 其他非侵入性 BBB 技术

欧洲血脑屏障技术市场 -通过应用

  • 阿尔茨海默病
  • 癫痫
  • 帕金森病
  • 多发性硬化症
  • 猎人综合症
  • 脑癌
  • 其他
  • >

欧洲血脑屏障技术市场 -按国家/地区

  • 英国
  • 德国
  • 法国
  • 意大利
  • 西班牙
  • < span>欧洲其他地区

欧洲血脑屏障技术市场 -提及的公司

  • 梯瓦制药工业有限公司                             ;       
  • F.霍夫曼拉罗氏有限公司                    ;           
  • 礼来公司和公司      ;                  &n公共服务提供商;                  &n公共服务提供商;          
  • 百时美施贵宝公司    ;                  &n公共服务提供商;                 
  • 辉瑞公司                                  ;                     ;                   
  • 强生公司约翰逊服务公司                  ;                   
  • Fabre-Kramer 制药公司                     
  • Bioasis Technologies, Inc.
  • Abliva AB。

TABLE OF CONTENTS

1.           Introduction

1.1         Scope of the Study

1.2         The Insight Partners Research Report Guidance

1.3         Market Segmentation

1.3.1        Europe Blood Brain Barrier Technologies Market – By Technology

1.3.2        Europe Blood Brain Barrier Technologies Market – By Application

1.3.3        Europe Blood Brain Barrier Technologies Market– By Country

2.           Europe Blood Brain Barrier Technologies Market – Key Takeaways

3.        Research Methodology

3.1         Coverage

3.2         Secondary Research

3.3         Primary Research

4.           Europe Blood Brain Barrier Technologies Market – Market Landscape

4.1         Overview

4.2         PEST Analysis

4.3         Experts Opinion

5.           Europe Blood Brain Barrier Technologies Market – Key Market Dynamics

5.1         Market Drivers

5.1.1        Up-surging Prevalence of Neurological Disorders

5.1.2        Raising Geriatric Population and Rising Prevalence of Age-Associated Neurological Disorders

5.2         Market Restraints

5.2.1        Problems in Brain Medication Delivery

5.3         Market Opportunities

5.3.1        High Number of Product Approvals and Launches

5.4         Future Trends

5.4.1        Scaling Demand of Nanoparticles for Brain Drug Delivery

5.5         Impact Analysis

6.           Europe Blood Brain Barrier Technologies – Market Analysis

6.1         Europe Blood Brain Barrier Technologies Market Revenue Forecast and Analysis

7.           Europe Blood Brain Barrier Technologies Market Analysis – by Technology

7.1         Overview

7.2         Blood Brain Barrier Technologies Market, by Technology 2021 & 2028 (%)

7.3         Bispecific Antibody RMT Approach

7.3.1        Overview

7.3.2        Bispecific Antibody RMT Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

7.4         Trojan Horse Approach

7.4.1        Overview

7.4.2        Trojan Horse Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

7.5         Increasing Permeability

7.5.1        Overview

7.5.2        Increasing Permeability: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

7.6         Passive Diffusion

7.6.1        Overview

7.6.2        Passive Diffusion: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

7.7         Other Non-Invasive BBB Technologies

7.7.1        Overview

7.7.2        Other Non-Invasive BBB Technologies: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.           Europe Blood Brain Barrier Technologies Market Analysis – By Application

8.1         Overview

8.2         Blood Brain Barrier Technologies Market, by Application 2021 & 2028 (%)

8.3         Alzheimer’s Disease

8.3.1        Overview

8.3.2        Alzheimer’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.4         Epilepsy

8.4.1        Overview

8.4.2        Epilepsy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.5         Parkinson’s Disease

8.5.1        Overview

8.5.2        Parkinson’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.6         Multiple Sclerosis

8.6.1        Overview

8.6.2        Multiple Sclerosis: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.7         Hunter’s Syndrome

8.7.1        Overview

8.7.2        Hunter’s Syndrome: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.8         Brain Cancer

8.8.1        Overview

8.8.2        Brain Cancer: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

8.9         Others

8.9.1        Overview

8.9.2        Others: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

9.           Europe Blood Brain Barrier Technologies Market – Country Analysis

9.1         Overview

9.1.1        Europe: Blood Brain Barrier Technologies Market, by Country, 2021 & 2028(%)

9.1.1.1          Germany: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.1.1          Germany: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.1.2          Germany: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)

9.1.1.1.3          Germany: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)

9.1.1.2          France: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.2.1          France: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.2.2          France: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)

9.1.1.2.3          France: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)

9.1.1.3          UK: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.3.1          UK: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.3.2          UK: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)

9.1.1.3.3          UK: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)

9.1.1.4          Italy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.4.1          Italy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.4.2          Italy: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)

9.1.1.4.3          Italy: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)

9.1.1.5          Spain: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.5.1          Spain: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.5.2          Spain: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)

9.1.1.5.3          Spain: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)

9.1.1.6          Rest of Europe: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.6.1          Rest of Europe: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

9.1.1.6.2          Rest of Europe: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)

9.1.1.6.3          Rest of Europe: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)

10.        Impact Of COVID-19 Pandemic on Europe Blood Brain Barrier Technologies Market

10.1      Impact Assessment of COVID-19 Pandemic

11.        Europe Blood Brain Barrier Technologies Market– Industry Landscape

11.1      Overview

11.2      Organic Developments

11.2.1     Overview

11.3      Inorganic Developments

11.3.1     Overview

12.        Company Profiles

12.1      Teva Pharmaceutical Industries Ltd.

12.1.1     Key Facts

12.1.2     Business Description

12.1.3     Products and Services

12.1.4     Financial Overview

12.1.5     SWOT Analysis

12.1.6     Key Developments

12.2      F. Hoffmann-La Roche Ltd.

12.2.1     Key Facts

12.2.2     Business Description

12.2.3     Products and Services

12.2.4     Financial Overview

12.2.5     SWOT Analysis

12.2.6     Key Developments

12.3      Eli Lilly and Company

12.3.1     Key Facts

12.3.2     Business Description

12.3.3     Products and Services

12.3.4     Financial Overview

12.3.5     SWOT Analysis

12.3.6     Key Developments

12.4      Bristol-Myers Squibb Company

12.4.1     Key Facts

12.4.2     Business Description

12.4.3     Products and Services

12.4.4     Financial Overview

12.4.5     SWOT Analysis

12.4.6     Key Developments

12.5      Pfizer, Inc.

12.5.1     Key Facts

12.5.2     Business Description

12.5.3     Products and Services

12.5.4     Financial Overview

12.5.5     SWOT Analysis

12.5.6     Key Developments

12.6      Johnson and Johnson Services, Inc.

12.6.1     Key Facts

12.6.2     Business Description

12.6.3     Products and Services

12.6.4     Financial Overview

12.6.5     SWOT Analysis

12.6.6     Key Developments

12.7      Fabre-Kramer Pharmaceuticals, Inc.

12.7.1     Key Facts

12.7.2     Business Description

12.7.3     Products and Services

12.7.4     Financial Overview

12.7.5     SWOT Analysis

12.7.6     Key Developments

12.8      Bioasis Technologies, Inc.

12.8.1     Key Facts

12.8.2     Business Description

12.8.3     Products and Services

12.8.4     Financial Overview

12.8.5     SWOT Analysis

12.8.6     Key Developments

12.9      Abliva AB.

12.9.1     Key Facts

12.9.2     Business Description

12.9.3     Products and Services

12.9.4     Financial Overview

12.9.5     SWOT Analysis

12.9.6     Key Developments

13.        Appendix

13.1      About The Insight Partners

13.2      Glossary of Terms

 


LIST OF TABLES

Table 1.             Europe Blood Brain Barrier Technologies Market – Revenue, and Forecast to 2028 (US$ Million)

Table 2.             Germany: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)

Table 3.             Germany: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)

Table 4.             France: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)

Table 5.             France: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)

Table 6.             UK: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)

Table 7.             UK: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)

Table 8.             Italy: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)

Table 9.             Italy: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)

Table 10.          Spain: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)

Table 11.          Spain: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)

Table 12.          Rest of Europe: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)

Table 13.          Rest of Europe: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)

Table 14.          Organic Developments Done By Companies

Table 15.          Inorganic Developments Done By Companies

Table 16.          Glossary of Terms, Blood Brain Barrier Technologies Market

 


LIST OF FIGURES

Figure 1.           Europe Blood Brain Barrier Technologies Market Segmentation

Figure 2.           Europe Blood Brain Barrier Technologies Market Segmentation, By Country

Figure 3.           Europe Blood Brain Barrier Technologies Market Overview

Figure 4.           Increasing Permeability Segment Held the Largest Share by Technology in Blood Brain Barrier Technologies Market

Figure 5.           U.K. to Show Significant Growth During Forecast Period

Figure 6.           Europe Blood Brain Barrier Technologies Market, Industry Landscape

Figure 7.           Europe and PEST Analysis

Figure 8.           Europe Blood Brain Barrier Technologies Market– Revenue Forecast and Analysis – 2021 - 2028

Figure 9.           Blood Brain Barrier Technologies Market, by Technology 2021 & 2028 (%)

Figure 10.        Bispecific Antibody RMT Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 11.        Trojan Horse Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 12.        Increasing Permeability: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 13.        Passive Diffusion: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 14.        Other Non-Invasive BBB Technologies: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 15.        Blood Brain Barrier Technologies Market, by Application 2021 & 2028 (%)

Figure 16.        Alzheimer’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 17.        Epilepsy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 18.        Parkinson’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 19.        Multiple Sclerosis: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 20.        Hunter’s Syndrome: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 21.        Brain Cancer: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 22.        Others: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)

Figure 23.        Europe: Blood Brain Barrier Technologies Market, by Key Country – Revenue (2021) (USD Million)

Figure 24.        Europe: Blood Brain Barrier Technologies Market, by Country, 2021 & 2028 (%)

Figure 25.        Germany: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

Figure 26.        France: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

Figure 27.        UK: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

Figure 28.        Italy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

Figure 29.        Spain: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

Figure 30.        Rest of Europe: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)

Figure 31.        Impact of COVID-19 Pandemic in European Country Markets

  1. Teva Pharmaceutical Industries Ltd.                                         
  2. F. Hoffmann-La Roche Ltd                                                            
  3. Eli Lilly and Company                                                                    
  4. Bristol-Myers Squibb Company                                                    
  5. Pfizer, Inc.                                                                                       
  6. Johnson & Johnson Services, Inc.                                               
  7. Fabre-Kramer Pharmaceuticals, Inc.                                          
  8. Bioasis Technologies, Inc.
  9. Abliva AB.
  • Save and reduce time carrying out entry-level research by identifying the growth, size, leading players and segments in the Europe blood brain barrier technologies market.                                      
  • Highlights key business priorities in order to assist companies to realign their business strategies
  • The key findings and recommendations highlight crucial progressive industry trends in the Europe blood brain barrier technologies market, thereby allowing players across the value chain to develop effective long-term strategies
  • Develop/modify business expansion plans by using substantial growth offering developed and emerging markets
  • Scrutinize in-depth Europe market trends and outlook coupled with the factors driving the blood brain barrier technologies market, as well as those hindering it
  • Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to client products, segmentation, pricing, and distribution  
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