South and Central America Non-Alcoholic Steatohepatitis Market Forecast to 2028 - COVID-19 Impact and Regional Analysis By Product (Vitamin E and Pioglitazone, Ocaliva, Elafibranor, Selonsertib, Cenicriviroc, and Others), Application (Treatment and Diagnosis), and Sales Channel (Hospital Pharmacy, Online Provider, and Retail Pharmacy)
The South & Central America Non-Alcoholic Steatohepatitis market is expected to reach US$ 303.88 million by 2028 from US$ 44.76 million in 2021. The market is estimated to grow at a CAGR of 31.5% from 2021 to 2028.
There is a growing trend in collaborations among pharmaceutical companies to broaden combination therapies. Monotherapy is probable to put up modest or equivocal data and, therefore, will now no longer be a powerful therapy. This is because of NASH’s complex pathophysiology (oxidant stress, inflammation activation, fibrogenesis, microbiome, increased intestinal perSAMbility, and immune cell mechanisms) that affect the heterogeneity of phenotypes. Hence, the improvement of a single therapy for NASH appears complex and unlikely, regardless of the plethora of later-stage trials because of the report. Several drugs are presently being tested with Farnesoid X receptor (FXR) agonists. For instance, the combinations of Tropifexor/CVC (Allergan and Novartis), Semaglutide/Cilofexor/Firsocostat (Novo Nordisk and Gilead), and Selonsertib/Cilofexor/Firsocostat (Gilead, now discontinued). Novartis is recruiting 380 NASH patients with stage 2 or 3 Clinical Research Network (CRN) fibrosis in other drug combination trials to evaluate Licogliflozin, an SGLT1/2 inhibitor, and Tropifexor in combination or alone with a Phase 2 ELIVATE clinical trial, that is anticipated to finish by 2023. Metacrine Inc. compares other FXR agonists, MET409, in a Phase 2a combination trial (ClinicalTrials.gov NCT04702490) with an SGLT2 inhibitor-Empagliflozin (Jardiance) in patients with NASH and T2D. Pfizer Inc has taken into consideration combination therapies as properly and assessed the impact of PF-06865571 (a DGAT2 inhibitor) and PF-05221304 (an ACC inhibitor) on whole-liver fats in subjects with NAFLD in comparison to placebo in a short, 6-week Phase 2a clinical trial (ClinicalTrials.gov NCT03776175). Both drugs alone and in combination considerably decreased liver fats compared to placebo; however, there is no evidence of additivity (or synergy) with no huge differences among each monotherapy compared with the combination therapy. By the end of 2020, Pfizer conveyed that PF-05221304 was no longer in its pipeline and was discontinued as a monotherapy. Furthermore, Pfizer recently included a Phase 1 clinical trial of their pipeline to evaluate PF-06882961 (Danuglipron), a GLP-1R agonist in combination with PF-06865571, for the treatment of NASH. Thus, growing clinical trials involving combination studies of drugs are expected to emerge as a trend in the forecast period.The South & Central America non-alcoholic steatohepatitis market is expected to grow at a good CAGR during the forecast period.
South & Central America Non-Alcoholic Steatohepatitis Revenue and Forecast to 2028 (US$ Million)
South & Central America Non-Alcoholic Steatohepatitis Market Segmentation
The South & Central America Non-Alcoholic Steatohepatitis market segmented into product, application, sales channel and country. Based on product type the South & Central America Non-Alcoholic Steatohepatitis market is segmented into vitamin e and pioglitazone, ocaliva, elafibranor, selonsertib,cenicriviroc and others. The selonsertib & cenicriviroc segment is expected to be the fastest growing segment over the forecaste period.Based on application the South & Central America Non-Alcoholic Steatohepatitis market segmented into treatment and diagnosis. The treatment segment is dominated South & Central America Non-Alcoholic Steatohepatitis market in 2020. Based on sales channel, the South & Central America Non-Alcoholic Steatohepatitis market segmented into hospital pharmacy, online provider, and retail pharmacy. The retail pharmacy segment is dominated South & Central America Non-Alcoholic Steatohepatitis market in 2020. Based on country, the South & Central America non-alcoholic steatohepatitis market is segmented into Brazil, Argentina, and the rest of South & Central America. The Brazil dominated the South & Central America non-alcoholic steatohepatitis market in 2020.
Cadila Pharmaceutical, Intercept Pharmaceutical, Novartis AG, Galmed Pharmaceutical, GENFIT, Siemens Healthineers AG, and Laboratory Corporation of America Holdings are among the leading companies in the South & Central America non-alcoholic steatohepatitis market.
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 SAM Non-Alcoholic Steatohepatitis Market – By Product
1.3.2 SAM Non-Alcoholic Steatohepatitis Market – By Application
1.3.3 SAM Non-Alcoholic Steatohepatitis Market – By Sales Channel
1.3.4 SAM Non-Alcoholic Steatohepatitis Market – By Country
2. Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. SAM Non-Alcoholic Steatohepatitis Market – Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 South And Central America PEST Analysis
4.3 Experts Opinion
5. SAM Non-alcoholic steatohepatitis (NASH) Market – Key Market Dynamics
5.1 Market Drivers
5.1.1 Rising Prevalence of NASH
5.1.2 Increasing Initiatives for the Awareness of NASH
5.2 Market Restraints
5.2.1 Lack of Established Guidelines in the Diagnosis and Management of NASH
5.2.2 Withdrawal of Drugs from Seeking Marketing Authorization for NASH
5.3 Market Opportunities
5.3.1 Growing Opportunities in Developing Nations
5.3.2 High Competition among Market Players to Manufacture the First Marketed NASH Drug Creates Global Sales Opportunity
5.4 Future Trends
5.4.1 Growing Clinical Trials Involving Combination Studies of Drugs
5.5 Impact Analysis
6. Non-alcoholic steatohepatitis (NASH) Market– SAM Analysis
6.1 SAM Non-Alcoholic Steatohepatitis Market Revenue Forecast and Analysis
7. SAM Non-alcoholic steatohepatitis (NASH) Market Revenue and Forecasts To 2028– by Product
7.1 Overview
7.2 Product Market Revenue and Forecast Analysis (US$ Mn)
7.3 Vitamin E and Pioglitazone
7.3.1 Overview
7.3.2 Vitamin E and Pioglitazone Revenue and Forecast to 2028 (US$ Mn)
7.4 Ocaliva
7.4.1 Overview
7.4.2 Ocaliva Revenue and Forecast to 2028 (US$ Mn)
7.5 Elafibranor
7.5.1 Overview
7.5.2 Elafibranor Revenue and Forecast to 2028 (US$ Mn)
7.6 Selonsertib & Cenicriviroc
7.6.1 Overview
7.6.2 Selonsertib Revenue and Forecast to 2028 (US$ Mn)
7.7 Others
7.7.1 Overview
7.7.2 Others Revenue and Forecast to 2028 (US$ Mn)
8. SAM Non-Alcoholic Steatohepatitis (NASH) Market Analysis and Forecast to 2028 – by Application
8.1 Overview
8.2 Application Market Revenue and Forecast Analysis (US$ Mn)
8.3 Treatment
8.3.1 Overview
8.3.2 Treatment Market Revenue and Forecast to 2028 (US$ Mn)
8.4 Diagnosis
8.4.1 Overview
8.4.2 Diagnosis Market Revenue and Forecast to 2028 (US$ Mn)
9. SAM Non-Alcoholic Steatohepatitis (NASH) Market Analysis and Forecast to 2028 – by Sales Channel
9.1 Overview
9.2 Sales Channel Market Revenue and Forecast Analysis (US$ Mn)
9.3 Hospital Pharmacy
9.3.1 Overview
9.3.2 Hospital Pharmacy Market Revenue and Forecast to 2028 (US$ Mn)
9.4 Retail Pharmacy
9.4.1 Overview
9.4.2 Retail Pharmacy Market Revenue and Forecast to 2028 (US$ Mn)
9.5 Online Provider
9.5.1 Overview
9.5.2 Online Provider Market Revenue and Forecast to 2028 (US$ Mn)
10. SAM Non-alcoholic steatohepatitis (NASH) Market Revenue and Forecasts to 2028 – Country Analysis
10.1 South and Central America Non-Alcoholic Steatohepatitis Market Revenue and Forecast To 2028
10.1.1 Overview
10.1.3 South and Central America: Non-Alcoholic Steatohepatitis Market, by Country, 2021 & 2028 (%)
10.1.3.1 Brazil: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
10.1.3.1.1 Brazil: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
10.1.3.1.2 Brazil: Non-Alcoholic Steatohepatitis Market , by Product, 2019–2028 (USD Million)
10.1.3.1.3 Brazil: Non-Alcoholic Steatohepatitis Market, by Application, 2019–2028 (USD Million)
10.1.3.1.4 Brazil: Non-Alcoholic Steatohepatitis Market, by Sales Channel, 2019–2028 (USD Million)
10.1.3.2 Argentina: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
10.1.3.2.1 Argentina: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
10.1.3.2.2 Argentina: Non-Alcoholic Steatohepatitis Market , by Product, 2019–2028 (USD Million)
10.1.3.2.3 Argentina: Non-Alcoholic Steatohepatitis Market , by Application, 2019–2028 (USD Million)
10.1.3.2.4 Argentina: Non-Alcoholic Steatohepatitis Market, by Sales Channel, 2019–2028 (USD Million)
10.1.3.3 Rest of South and Central America: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
10.1.3.3.1 Rest of South and Central America: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
10.1.3.3.2 Rest of South and Central America: Non-Alcoholic Steatohepatitis Market , by Product, 2019–2028 (USD Million)
10.1.3.3.3 Rest of South and Central America: Non-Alcoholic Steatohepatitis Market , by Application, 2019–2028 (USD Million)
10.1.3.3.4 Rest of South and Central America: Non-Alcoholic Steatohepatitis Market , by Sales Channel, 2019–2028 (USD Million)
11. Industry Landscape
11.1 Overview
11.2 Organic Developments
11.2.1 Overview
11.3 Inorganic Developments
11.3.1 Overview
12. Company Profiles
12.1 Cadila Pharmaceuticals Ltd.
12.1.1 Key Facts
12.1.2 Business Description
12.1.3 Products and Services
12.1.4 Financial Overview
12.1.5 SWOT Analysis
12.1.6 Key Developments
12.2 Intercept Pharmaceuticals, Inc
12.2.1 Key Facts
12.2.2 Business Description
12.2.3 Products and Services
12.2.4 Financial Overview
12.2.5 SWOT Analysis
12.2.6 Key Developments
12.3 Novartis AG
12.3.1 Key Facts
12.3.2 Business Description
12.3.3 Products and Services
12.3.4 Financial Overview
12.3.5 SWOT Analysis
12.3.6 Key Developments
12.4 Galmed Pharmaceuticals.
12.4.1 Key Facts
12.4.2 Business Description
12.4.3 Products and Services
12.4.4 Financial Overview
12.4.5 SWOT Analysis
12.4.6 Key Developments
12.5 GENFIT.
12.5.1 Key Facts
12.5.2 Business Description
12.5.3 Products and Services
12.5.4 Financial Overview
12.5.5 SWOT Analysis
12.5.6 Key Developments
12.6 Siemens Healthineers AG
12.6.1 Key Facts
12.6.2 Business Description
12.6.3 Products and Services
12.6.4 Financial Overview
12.6.5 SWOT Analysis
12.6.6 Key Developments
12.7 Laboratory Corporation of America Holdings
12.7.1 Key Facts
12.7.2 Business Description
12.7.3 Products and Services
12.7.4 Financial Overview
12.7.5 SWOT Analysis
12.7.6 Key Developments
13. Appendix
13.1 About The Insight Partners
13.2 Glossary of Terms
LIST OF TABLES
Table 1. Brazil: Non-Alcoholic Steatohepatitis Market , by Product – Revenue and Forecast to 2028 (USD Million)
Table 2. Brazil: Non-Alcoholic Steatohepatitis Market, by Application– Revenue and Forecast to 2028 (USD Million)
Table 3. Brazil: Non-Alcoholic Steatohepatitis Market, by Sales Channel– Revenue and Forecast to 2028 (USD Million)
Table 4. Argentina: Non-Alcoholic Steatohepatitis Market , by Product – Revenue and Forecast to 2028 (USD Million)
Table 5. Argentina: Non-Alcoholic Steatohepatitis Market , by Application– Revenue and Forecast to 2028 (USD Million)
Table 6. Argentina: Non-Alcoholic Steatohepatitis Market , by Sales Channel– Revenue and Forecast to 2028 (USD Million)
Table 7. Rest of South and Central America: Non-Alcoholic Steatohepatitis Market , by Product – Revenue and Forecast to 2028 (USD Million)
Table 8. Rest of South and Central America: Non-Alcoholic Steatohepatitis Market , by Application– Revenue and Forecast to 2028 (USD Million)
Table 9. Rest of South and Central America: Non-Alcoholic Steatohepatitis Market , by Sales Channel– Revenue and Forecast to 2028 (USD Million)
Table 10. Organic Developments Done By Companies
Table 11. Inorganic Developments Done By Companies
Table 12. Glossary of Terms
LIST OF FIGURES
Figure 1. SAM Non-Alcoholic Steatohepatitis Market Segmentation
Figure 2. SAM Non-Alcoholic Steatohepatitis Market, By Country
Figure 3. SAM Non-Alcoholic Steatohepatitis Market Overview
Figure 4. SAM Non-Alcoholic Steatohepatitis Market, By Application
Figure 5. SAM Non-Alcoholic Steatohepatitis Market, By Country
Figure 6. South And Central America: PEST Analysis
Figure 7. SAM Experts Opinion
Figure 8. SAM Non-Alcoholic Steatohepatitis (NASH) Market Impact Analysis of Drivers and Restraints
Figure 9. SAM Non-Alcoholic Steatohepatitis Market– Revenue Forecast and Analysis
Figure 10. SAM Product Market Analysis and Forecast 2021 and 2028 (%)
Figure 11. SAM Vitamin E and Pioglitazone Revenue and Forecast to 2028 (US$ Mn)
Figure 12. SAM Ocaliva Revenue and Forecast to 2028 (US$ Mn)
Figure 13. SAM Elafibranor Revenue and Forecast to 2028 (US$ Mn)
Figure 14. SAM Selonsertib Revenue and Forecast to 2028 (US$ Mn)
Figure 15. SAM Others Revenue and Forecast to 2028 (US$ Mn)
Figure 16. SAM Application Market Analysis and Forecast 2021 and 2028 (%)
Figure 17. SAM Treatment Market Revenue and Forecast to 2028 (US$ Mn)
Figure 18. SAM Diagnosis Market Revenue and Forecast to 2028 (US$ Mn)
Figure 19. SAM Sales Channel Market Analysis and Forecast 2021 and 2028 (%)
Figure 20. SAM Hospital Pharmacy Market Revenue and Forecast to 2028 (US$ Mn)
Figure 21. SAM Retail Pharmacy Market Revenue and Forecast to 2028 (US$ Mn)
Figure 22. SAM Online Provider Market Revenue and Forecast to 2028 (US$ Mn)
Figure 23. South and Central America: Non-Alcoholic Steatohepatitis Market, by Key Country – Revenue (2021) (USD Million)
Figure 24. South and Central America: Non-Alcoholic Steatohepatitis Market, by Country, 2021 & 2028 (%)
Figure 25. Brazil: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
Figure 26. Argentina: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
Figure 27. Rest of South and Central America: Non-Alcoholic Steatohepatitis Market – Revenue and Forecast to 2028 (USD Million)
- Cadila Pharmaceutical.
- Intercept Pharmaceutical.
- Novartis AG.
- Galmed Pharmaceutical.
- GENFIT.
- Siemens Healthineers AG.
- Laboratory Corporation of America Holdings.
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- Scrutinize in-depth South & Central America market trends and outlook coupled with the factors driving the non-alcoholic steatohepatitis, as well as those hindering it.
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