South America Blood Brain Barrier Technologies Market Forecast to 2028 - COVID-19 Impact and Regional Analysis By Technology (Bispecific Antibody RMT Approach, Trojan Horse Approach, Increasing Permeability, Passive Diffusion, and Other Non-Invasive BBB Technologies) and Application (Alzheimer’s Disease, Epilepsy, Parkinson’s Disease, Multiple Sclerosis, Hunter’s Syndrome, Brain Cancer, and Others)
Market Introduction
South America region consists of Brazil, Argentina, and rest of SAM. Brazil is expected to have the major market share in this region. Brazil is the fifth largest country in the world both by area and by population and experiencing the fastest demographic aging worldwide and aging population develops age related neurodegenerative disorders, which is likely to increase the demand for the pulmonary devices in the country. In Brazil, the aging population is at a rapid pace and in a context of regional and historical socioeconomic inequalities. According to the study conducted in Brazil, the community of women estimated at the vast majority with 16.9 million (56%) of elderly persons, whereas older adults estimated approx. 13.3 million (44%). The prevalence of neurodegenerative disorders has been linked with the aging population in Brazil. Estimates from the Brazilian Institute of Geography and Statistics (IBGE) indicate that, by 2060, people over 65 years old will account for 25.5% of the population. The blood brain barrier technologies Market is being influenced by factors such as the increasing prevalence of brain cancer. For instance, as per Globocan 2020 report, brain cancer is the most common cause of death in Brazil. There were 12 260 new cases of brain cancer in Brazil in 2020 and 10 920 deaths due to brain and CNS cancers. This is likely to demand blood brain barrier technologies in Brazil. Similarly, 5 years prevalence rate for brain cancer in Brazil for all ages is around 15.17 per 100 000 population. In Brazil, the ischemic stroke is the common type of neurovascular diseases, accounting 61.8% of total deaths in 2016. This data was published by a study titled as ‘The burden of stroke in Brazil in 2016: an analysis of the Global Burden of Disease study findings’ it also stated that percentage was higher among the people aged 70 years and above. However, the mortality rates due to stroke have been reduced in the country. The development and improvements in the country have led to easy access to education and technology. Also, the advancement in primary health care has focused on prevention of the stroke and other neurological disorder.
The presence of various developing countries in South America makes this region one of the key markets for the future growth of the blood brain barrier technologies market. The growing population, rising disposable income, growing awareness related to daily health diagnostics, and rise in prevalence of neurological diseases are some of the key factors that are expected to drive the growth and demand for blood brain barrier technologies treatment in this region. However, the high number of confirmed cases and deaths due to COVID-19 in major South American countries such as Brazil, Peru, Chile, Ecuador, and Argentina are anticipated to affect the market demand in these countries. Headache, fever, anosmia, ageusia, as well as encephalitis, Guillain-Barre syndrome, and ischemic stroke have all been linked to infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2, which is responsible for the current coronavirus disease (COVID-19) pandemic, can enter and affect the central nervous system (CNS) through a variety of routes, including axonal retrograde transport or interactions with the blood-brain barrier (BBB) or blood-cerebrospinal fluid (CSF) barrier. It observed low replication of SARS-CoV-2 that was accompanied by a very moderate inflammatory response. All these factors are expected to positive impact the growth of blood brain barrier technologies market in this region in the coming quarters.
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Market Overview and Dynamics
The blood brain barrier technologies market in South America is expected to grow from US$ 297.18 million by 2028 from US$ 64.02 million in 2021. The market is estimated to grow at a CAGR of 24.5% from 2021 to 2028. Nanomedicine is a rapidly developing field with nanoparticles or nanostructures for medical applications, particularly in the underdeveloped area of drug delivery to the brain. Great expectations are placed on the ability of multifunctional nanoparticles (NPs) to cross the blood-brain barrier. Recent advances in nanotechnology allow otherwise poorly distributed drugs in the brain to be packaged into nanoparticles with brain-targeting properties. These targeted carrier systems enhance the delivery of drugs by entrapping or encapsulating the drug in the particle with a targeting peptide/ligand on its surface that results in BBB targeting. These carrier systems cross the BBB using transcellular pathways such as receptor-mediated endocytosis. A significant advantage of solid lipid nanoparticles is that their high lipid solubility physically stabilizes the nanoparticles, which increases the carrying capacity of the drug and results in a controlled release rate of the drug. Although lipid-based nanoparticles and formulations have a prolonged systemic circulation time and increased tumor retention due to increased permeation and retention, their most important limiting factor is rapid clearance from the bloodstream through the reticuloendothelial system. Several groups are working to improve targeting to the brain by mounting nanoparticles with ligands, which are substrates for BBB uptake transporters, facilitating transit to the brain. As this technology advances, this system can effectively deliver a variety of therapeutic agents with a favorable toxicity profile. Thus, the use of nanoparticles for brain drug delivery is expected to be the trend during the forecast period.
Key Market Segments
In terms of technology, the increasing permeability segment accounted for the largest share of the South America blood brain barrier technologies market in 2021. In terms of application, the parkinson’s disease segment accounted for the largest share of the South America blood brain barrier technologies market in 2021.
Major Sources and Companies Listed
A few major primary and secondary sources referred to for preparing this report on the blood brain barrier technologies market in South America are company websites, annual reports, financial reports, national government documents, and statistical database, among others. Major companies listed in the report are Teva Pharmaceutical Industries Ltd.; F. Hoffmann-La Roche Ltd.; Eli Lilly and Company; Bristol-Myers Squibb Company; Pfizer, Inc.; and Johnson & Johnson Services, Inc. among others.
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South America Blood Brain Barrier Technologies Market Segmentation
South America Blood Brain Barrier Technologies Market – By Technology
- Bispecific Antibody RMT Approach
- Trojan Horse Approach
- Increasing Permeability
- Passive Diffusion
- Other Non-Invasive BBB Technologies
South America Blood Brain Barrier Technologies Market – By Application
- Alzheimer’s Disease
- Epilepsy
- Parkinson’s Disease
- Multiple Sclerosis
- Hunter’s Syndrome
- Brain Cancer
- Others
South America Blood Brain Barrier Technologies Market – By Country
- Brazil
- Argentina
- Rest of SAM
South America Blood Brain Barrier Technologies Market – Companies Mentioned
- Teva Pharmaceutical Industries Ltd.
- F. Hoffmann-La Roche Ltd
- Eli Lilly and Company
- Bristol-Myers Squibb Company
- Pfizer, Inc.
- Johnson & Johnson Services, Inc.
TABLE OF CONTENTS
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 South America Blood Brain Barrier Technologies Market – By Technology
1.3.2 South America Blood Brain Barrier Technologies Market – By Application
1.3.3 South America Blood Brain Barrier Technologies Market– By Country
2. South America Blood Brain Barrier Technologies Market – Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. South America Blood Brain Barrier Technologies Market– Market Landscape
4.1 Overview
4.2 PEST Analysis
4.3 Experts Opinion
5. South America Blood Brain Barrier Technologies Market – Key Market Dynamics
5.1 Market Drivers
5.1.1 Boosting Prevalence of Neurological Disorders
5.1.2 Accelerating Geriatric Population and Rising Prevalence of Age-Associated Neurological Disorders
5.2 Market Restraints
5.2.1 Barriers in Brain Medication Delivery
5.3 Market Opportunities
5.3.1 Elevating Number of Product Approvals and Launches
5.4 Future Trends
5.4.1 Surging Demand Nanoparticles for Brain Drug Delivery
5.5 Impact Analysis
6. South America Blood Brain Barrier Technologies – Market Analysis
6.1 South America Blood Brain Barrier Technologies Market Revenue Forecast and Analysis
7. South America Blood Brain Barrier Technologies Market Analysis – by Technology
7.1 Overview
7.2 South America Blood Brain Barrier Technologies Market, by Technology 2021 & 2028 (%)
7.3 Bispecific Antibody RMT Approach
7.3.1 Overview
7.3.2 Bispecific Antibody RMT Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
7.4 Trojan Horse Approach
7.4.1 Overview
7.4.2 Trojan Horse Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
7.5 Increasing Permeability
7.5.1 Overview
7.5.2 Increasing Permeability: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
7.6 Passive Diffusion
7.6.1 Overview
7.6.2 Passive Diffusion: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
7.7 Other Non-Invasive BBB Technologies
7.7.1 Overview
7.7.2 Other Non-Invasive BBB Technologies: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8. South America Blood Brain Barrier Technologies Market Analysis – By Application
8.1 Overview
8.2 South America Blood Brain Barrier Technologies Market, by Application 2021 & 2028 (%)
8.3 Alzheimer’s Disease
8.3.1 Overview
8.3.2 Alzheimer’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8.4 Epilepsy
8.4.1 Overview
8.4.2 Epilepsy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8.5 Parkinson’s Disease
8.5.1 Overview
8.5.2 Parkinson’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8.6 Multiple Sclerosis
8.6.1 Overview
8.6.2 Multiple Sclerosis: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8.7 Hunter’s Syndrome
8.7.1 Overview
8.7.2 Hunter’s Syndrome: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8.8 Brain Cancer
8.8.1 Overview
8.8.2 Brain Cancer: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
8.9 Others
8.9.1 Overview
8.9.2 Others: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
9. South America Blood Brain Barrier Technologies Market – Country Analysis
9.1 Overview
9.1.1 South America: Blood Brain Barrier Technologies Market, by Country, 2021 & 2028 (%)
9.1.1.1 Brazil: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
9.1.1.1.1 Brazil: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
9.1.1.1.2 Brazil: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)
9.1.1.1.3 Brazil: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)
9.1.1.2 Argentina: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
9.1.1.2.1 Argentina: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
9.1.1.2.2 Argentina: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)
9.1.1.2.3 Argentina: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)
9.1.1.3 Rest of South America: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
9.1.1.3.1 Rest of South America: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
9.1.1.3.2 Rest of South America: Blood Brain Barrier Technologies Market, by Technology, 2019–2028 (USD Million)
9.1.1.3.3 Rest of South America: Blood Brain Barrier Technologies Market, by Application, 2019–2028 (USD Million)
10. Impact Of COVID-19 Pandemic on South America Blood Brain Barrier Technologies Market
10.1 Impact Assessment of COVID-19 Pandemic
11. South America Blood Brain Barrier Technologies Market– Industry Landscape
11.1 Overview
11.2 Organic Developments
11.2.1 Overview
11.3 Inorganic Developments
11.3.1 Overview
12. Company Profiles
12.1 Teva Pharmaceutical Industries Ltd.
12.1.1 Key Facts
12.1.2 Business Description
12.1.3 Products and Services
12.1.4 Financial Overview
12.1.5 SWOT Analysis
12.1.6 Key Developments
12.2 F. Hoffmann-La Roche Ltd.
12.2.1 Key Facts
12.2.2 Business Description
12.2.3 Products and Services
12.2.4 Financial Overview
12.2.5 SWOT Analysis
12.2.6 Key Developments
12.3 Eli Lilly and Company
12.3.1 Key Facts
12.3.2 Business Description
12.3.3 Products and Services
12.3.4 Financial Overview
12.3.5 SWOT Analysis
12.3.6 Key Developments
12.4 Bristol-Myers Squibb Company
12.4.1 Key Facts
12.4.2 Business Description
12.4.3 Products and Services
12.4.4 Financial Overview
12.4.5 SWOT Analysis
12.4.6 Key Developments
12.5 Pfizer, Inc.
12.5.1 Key Facts
12.5.2 Business Description
12.5.3 Products and Services
12.5.4 Financial Overview
12.5.5 SWOT Analysis
12.5.6 Key Developments
12.6 Johnson and Johnson Services, Inc.
12.6.1 Key Facts
12.6.2 Business Description
12.6.3 Products and Services
12.6.4 Financial Overview
12.6.5 SWOT Analysis
12.6.6 Key Developments
13. Appendix
13.1 About The Insight Partners
13.2 Glossary of Terms
LIST OF TABLES
Table 1. South America Blood Brain Barrier Technologies Market – Revenue, and Forecast to 2028 (US$ Million)
Table 2. Brazil: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)
Table 3. Brazil: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)
Table 4. Argentina: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)
Table 5. Argentina: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)
Table 6. Rest of South America: Blood Brain Barrier Technologies Market, by Technology – Revenue and Forecast to 2028 (USD Million)
Table 7. Rest of South America: Blood Brain Barrier Technologies Market, by Application – Revenue and Forecast to 2028 (USD Million)
Table 8. Organic Developments Done By Companies
Table 9. Inorganic Developments Done By Companies
Table 10. Glossary of Terms, Blood Brain Barrier Technologies Market
LIST OF FIGURES
Figure 1. South America Blood Brain Barrier Technologies Market Segmentation
Figure 2. South America Blood Brain Barrier Technologies Market Segmentation, By Country
Figure 3. South America Blood Brain Barrier Technologies Market Overview
Figure 4. Increasing Permeability Segment Held the Largest Share by Technology in Blood Brain Barrier Technologies Market
Figure 5. Brazil to Show Significant Growth during the Forecast Period
Figure 6. South America Blood Brain Barrier Technologies Market, Industry Landscape
Figure 7. South America (SAM) PEST Analysis
Figure 8. South America Blood Brain Barrier Technologies Market– Revenue Forecast and Analysis – 2021 - 2028
Figure 9. South America Blood Brain Barrier Technologies Market, by Technology 2021 & 2028 (%)
Figure 10. Bispecific Antibody RMT Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 11. Trojan Horse Approach: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 12. Increasing Permeability: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 13. Passive Diffusion: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 14. Other Non-Invasive BBB Technologies: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 15. South America Blood Brain Barrier Technologies Market, by Application 2021 & 2028 (%)
Figure 16. Alzheimer’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 17. Epilepsy: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 18. Parkinson’s Disease: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 19. Multiple Sclerosis: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 20. Hunter’s Syndrome: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 21. Brain Cancer: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 22. Others: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (US$ Million)
Figure 23. South America: Blood Brain Barrier Technologies Market, by Key Country – Revenue (2021) (USD Million)
Figure 24. South America: Blood Brain Barrier Technologies Market, by Country, 2021 & 2028 (%)
Figure 25. Brazil: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
Figure 26. Argentina: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
Figure 27. Rest of South America: Blood Brain Barrier Technologies Market – Revenue and Forecast to 2028 (USD Million)
Figure 28. Impact Of COVID-19 Pandemic in South America Country Markets- Teva Pharmaceutical Industries Ltd.
- F. Hoffmann-La Roche Ltd
- Eli Lilly and Company
- Bristol-Myers Squibb Company
- Pfizer, Inc.
- Johnson & Johnson Services, Inc.
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