North America Antibody Drug Conjugates Market

Historic Data: 2020-2021   |   Base Year: 2022   |   Forecast Period: 2023-2030

Analysis - By Technology (Cleavable Linker and Non-cleavable Linker), Application (Blood Cancer, Breast Cancer, Ovarian Cancer, Urothelial Cancer, and Others), and Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)

No. of Pages: 100
Report Code: BMIRE00029767
Category: Life Sciences
North America Antibody Drug Conjugates Market
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The North America antibody drug conjugates market was valued at US$ 3,659.81 million in 2022 and is expected to reach US$ 13,681.58 million by 2030; it is estimated to grow at a CAGR of 17.9% from 2022 to 2030.

Increasing FDA Approvals for ADCs Fuels the North America Antibody Drug Conjugates Market

 

According to an article, ‘An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy,’ published in the National Library of Medicine in September 2021, there were eight approvals for ADC in 2017, and it increased to 11 in September 2021. The FDA has approved a few more ADCs, including Lumoxiti, till the end of November 2022. Worldwide, more than 50 biopharmaceutical companies are involved in developing ADCs. The companies have targeted mainly blood cancer and other cancer types, such as lung, bladder, and gynecological tumors. Additionally, in June 2021, Evercore, a US-based Investment Banking and Evercore ISI, estimated that by 2030, the companies will sell ADCs for over US$ 20 billion annually. The increasing approvals and commercialization of ADCs are leading to significant market growth. Below is a list of FDA-approved ADCs.

List of FDA-Approved ADCs

Sr. No.

Company

Trade Name

ADC Drug

Cancer Type

Approval Year

1

Pfizer/Wyeth

Mylotarg

Gemtuzumab ozogamicin

Relapsed Acute Myelogenous Leukemia (AML)

2000; 2017

2

Seagen Genetics, Millennium/Takeda

Adcetris

Brentuximab vedotin

Relapsed HL and Relapsed sALCL

2011

3

Genentech, Roche

Kadcyla

Trastuzumab emtansine

HER2-positive Metastatic Breast Cancer (mBC)

2013

4

Pfizer/Wyeth

Besponsa

Inotuzumab ozogamicin

Relapsed or Refractory CD22-positive B-cell Precursor Acute Lymphoblastic Leukemia

2017

5

Astrazeneca

Lumoxiti

Moxetumomab pasudotox

Relapsed or refractory hairy cell leukaemia (HCL) in adults

2018

6

Genentech, Roche

Polivy

Polatuzumab vedotin-piiq

Relapsed or refractory diffuse large B-cell lymphoma (DLBCL)

2019

7

Astellas/Seagen Genetics

Padcev

Enfortumab vedotin

Metastatic urothelial cancer in adult who have received a PD-1 or PD-L1 inhibitor, and a Pt-containing therapy

2019

8

AstraZeneca/Daiichi Sankyo

Enhertu

Trastuzumab deruxtecan

Metastatic HER2-positive breast cancer in adults, received two or more prior anti-HER2 based regimens

2019

9

Immunomedics

Trodelvy

Sacituzumab govitecan

Metastatic triple-negative breast cancer (mTNBC) in adults, and patients received minimum two prior therapies for patients with relapsed or refractory metastatic disease

2020

10

GlaxoSmithKline (GSK)

Blenrep

Belantamab mafodotin-blmf

Relapsed or refractory multiple myeloma in adults

2020, withdrawn on 22 Nov. 2022 in the US.

11

ADC Therapeutics

Zynlonta

Loncastuximab tesirine-lpyl

Large B-cell lymphoma

2021

12

Seagen Inc

Tivdak

Tisotumab vedotin-tftv

Recurrent or metastatic cervical cancer

2021

13

ImmunoGen

Elahere

Mirvetuximab soravtansine

Platinum-resistant ovarian cancer

2022

 

North America Antibody Drug Conjugates Market Overview

 

The antibody drug conjugates (ADCs) market in North America is analyzed based on the US, Canada, and Mexico. The market growth in the region is attributed to increasing research and development for ADCs, rising product approvals, growing awareness about ADCs, and rising number of mergers, collaborations, and partnerships among the operating players. In addition, significantly growing incidences of cancer are among the other leading factors escalating the demand for ADCs.

Furthermore, growing partnerships among the companies to expand their technologies in different regions enable market growth. In August 2023, ImmunoGen, Inc. and Takeda Pharmaceutical Company Limited collaborated to develop and commercialize ELAHERE, Immunogen’s ADC therapy, in Japan. Under the collaboration agreement, ImmunoGen, Inc. receives upfront and additional payments upon conversion of FDA accelerated approval of ELAHERE to treat platinum-resistant ovarian cancer. If Takeda achieves certain regulatory and commercial milestones and double-digit royalties through the net sales of ELAHERE in Japan, it will pay an additional payment to ImmunoGen, Inc. Nevertheless, Immunogen has retained its exclusive production rights and will supply the product for development and commercialization in Japan. In return, Takeda will be responsible for all regulatory filing and have an exclusive license to develop and commercialize ELAHERE in Japan.

 

North America Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Million)

North America Antibody Drug Conjugates Market Revenue and Forecast to 2030 (US$ Million)

 

North America Antibody Drug Conjugates Market Segmentation

 

The North America antibody drug conjugates market is segmented based on technology, application, distribution channel, and country.

 

Based on technology, the North America antibody drug conjugates market antibody drug conjugates market is bifurcated into cleavable linker and non-cleavable linker. The cleavable linker segment held a larger share in 2022.

 

Based on application, the North America antibody drug conjugates market antibody drug conjugates market is segmented into blood cancer, breast cancer, ovarian cancer, urothelial cancer, and others. The breast cancer segment held the largest share in 2022.

 

Based on distribution channel, the North America antibody drug conjugates market antibody drug conjugates market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment held the largest share in 2022.

Based on country, the North America antibody drug conjugates market is categorized into US, Canada, and Mexico. The US dominated the North America antibody drug conjugates market in 2022.

 

ADC Therapeutics SA, Pfizer Inc, Hoffmann-La Roche Ltd, ImmunoGen, Inc, GSK Plc, Gilead Sciences Inc, AstraZeneca Plc, Astellas Pharma Inc, RemeGen Co Ltd, and Takeda Pharmaceutical Co Ltd are some of the leading companies operating in the North America antibody drug conjugates market.   

North America Antibody Drug Conjugates Market Strategic Insights

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North America Antibody Drug Conjugates Market Segmentation Analysis

North America Antibody Drug Conjugates Market Report Highlights

North America Antibody Drug Conjugates Report Scope

Report Attribute Details
Market size in 2022 US$ 3,659.81 Million
Market Size by 2030 US$ 13,681.58 Million
CAGR (2022 - 2030) 17.9%
Historical Data 2020-2021
Forecast period 2023-2030
Segments Covered By Technology
  • Cleavable Linker
  • Non-cleavable Linker
By Application
  • Blood Cancer
  • Breast Cancer
  • Ovarian Cancer
  • Urothelial Cancer
By Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
Regions and Countries Covered North America
  • US
  • Canada
  • Mexico
Market leaders and key company profiles
  • ADC Therapeutics SA
  • Pfizer Inc
  • Hoffmann-La Roche Ltd
  • ImmunoGen Inc
  • GSK Plc
  • Gilead Sciences Inc
  • AstraZeneca Plc
  • Astellas Pharma Inc
  • RemeGen Co Ltd
  • Takeda Pharmaceutical Co Ltd
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North America Antibody Drug Conjugates Market Country and Regional Insights

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The List of Companies - North America Antibody Drug Conjugates Market

1. ADC Therapeutics SA
2. Pfizer Inc
3. Hoffmann-La Roche Ltd
4. ImmunoGen Inc
5. GSK Plc
6. Gilead Sciences Inc
7. AstraZeneca Plc
8. Astellas Pharma Inc
9. RemeGen Co Ltd
10. Takeda Pharmaceutical Co Ltd

Frequently Asked Questions
How big is the North America Antibody Drug Conjugates Market?

The North America Antibody Drug Conjugates Market is valued at US$ 3,659.81 Million in 2022, it is projected to reach US$ 13,681.58 Million by 2030.

What is the CAGR for North America Antibody Drug Conjugates Market by (2022 - 2030)?

As per our report North America Antibody Drug Conjugates Market, the market size is valued at US$ 3,659.81 Million in 2022, projecting it to reach US$ 13,681.58 Million by 2030. This translates to a CAGR of approximately 17.9% during the forecast period.

What segments are covered in this report?

The North America Antibody Drug Conjugates Market report typically cover these key segments-

  • Technology (Cleavable Linker, Non-cleavable Linker)
  • Application (Blood Cancer, Breast Cancer, Ovarian Cancer, Urothelial Cancer)
  • Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies)

What is the historic period, base year, and forecast period taken for North America Antibody Drug Conjugates Market?

The historic period, base year, and forecast period can vary slightly depending on the specific market research report. However, for the North America Antibody Drug Conjugates Market report:

  • Historic Period : 2020-2021
  • Base Year : 2022
  • Forecast Period : 2023-2030
  • Who are the major players in North America Antibody Drug Conjugates Market?

    The North America Antibody Drug Conjugates Market is populated by several key players, each contributing to its growth and innovation. Some of the major players include:

  • ADC Therapeutics SA
  • Pfizer Inc
  • Hoffmann-La Roche Ltd
  • ImmunoGen Inc
  • GSK Plc
  • Gilead Sciences Inc
  • AstraZeneca Plc
  • Astellas Pharma Inc
  • RemeGen Co Ltd
  • Takeda Pharmaceutical Co Ltd
  • Who should buy this report?

    The North America Antibody Drug Conjugates Market report is valuable for diverse stakeholders, including:

    • Investors: Provides insights for investment decisions pertaining to market growth, companies, or industry insights. Helps assess market attractiveness and potential returns.
    • Industry Players: Offers competitive intelligence, market sizing, and trend analysis to inform strategic planning, product development, and sales strategies.
    • Suppliers and Manufacturers: Helps understand market demand for components, materials, and services related to concerned industry.
    • Researchers and Consultants: Provides data and analysis for academic research, consulting projects, and market studies.
    • Financial Institutions: Helps assess risks and opportunities associated with financing or investing in the concerned market.

    Essentially, anyone involved in or considering involvement in the North America Antibody Drug Conjugates Market value chain can benefit from the information contained in a comprehensive market report.

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