Middle East & Africa Epilepsy Market Forecast to 2030 - Regional Analysis - by Type (Progressive Myoclonic Epilepsy, Reflex Epilepsy, Generalized Epilepsy, and Other), Route of Administration (Oral, Parenteral, and Others), Treatment Type (First Generation Drugs, Second Generation Drugs, and Third Generation Drugs), Age Group (Adult and Children), and Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Others)

BMIRE00030765 | Pages: 139 | Pharmaceuticals | Sep 2024 | Type: Regional | Status: Published

The Middle East & Africa epilepsy market was valued at US$ 456.34 million in 2022 and is expected to reach US$ 568.00 million by 2030; it is estimated to register a CAGR of 2.8% from 2022 to 2030.

Gene Therapy as Promising Treatment Approach Bolsters Middle East & Africa Epilepsy Market

Gene therapies are being explored as potential treatment options for certain genetic epilepsies. This innovative approach is aimed at treating diseases by modifying or manipulating the genetic makeup of cells. The fundamental principle of gene therapy is to correct or replace faulty genes that contribute to the development or progression of a particular condition. Since epileptic seizures are caused by excessive brain cell activity (neurons) in particular parts of the organ, targeting these neurons and turning them off could help prevent seizures. Two standard gene therapy techniques that can be employed to design an epilepsy treatment are gene addition and gene editing. Gene addition involves adding genetic material to an individual's cells to balance a missing or abnormal gene, while gene editing involves treating genetic epilepsy by directly modifying an individual's gene. By targeting specific genes associated with epilepsy and manipulating cellular genetic material, gene therapy can help restore normal cellular function and inhibit seizure generation.

Examining the genetic causes of a condition allows healthcare providers to offer more personalized and targeted treatment approaches. In cases involving heritable mutations, this knowledge aids in understanding the risks for affected families and facilitates genetic counseling, followed by informed decision-making. Ongoing advancements in the identification of genetic factors causing epilepsy to play a crucial role in guiding the medical care and management of affected individuals. Next-generation sequencing has largely driven significant progress in the field of genetics. This high-throughput genetic sequencing technique enables a faster and more comprehensive analysis of DNA, thereby aiding the identification of genetic causes of conditions such as epilepsy.

The continued progress in genetic research holds the potential to improve the care and support provided to individuals with epilepsy and their families. By targeting genes associated with ion channels, neurotransmitter receptors, or cellular signaling pathways, researchers can investigate how alterations in these genes contribute to epileptogenesis.

Although gene therapy for epilepsy is still in the early stages of development, preclinical studies in animal models have shown promising results. Animal models with specific epilepsy-related genetic mutations have been treated using gene therapy approaches, resulting in reduced seizure frequency and improved seizure control. In December 2023, UCL Queen Square Institute of Neurology researchers developed a new gene therapy to cure a devastating form of childhood epilepsy, which has been shown to notably reduce seizures in mice. They assessed a gene therapy based on the overexpression of a potassium channel that controls neuronal excitability in a mouse model with focal cortical dysplasia in the frontal lobe. The researchers injected an engineered potassium channel gene termed EKC into the affected frontal lobe of epileptic mice. They employed a virus lacking replicability as a vector to carry the potassium channel gene. The researchers found that gene therapy lowered seizures by an average of 87% compared to the control group without altering the mouse's memory or behavior. Taking into account the unmet needs in epilepsy therapeutics, it can be utilized to treat children who are severely affected by uncontrolled seizures.

Many gene therapy trials for the treatment of epilepsy are currently underway or in the planning stages. The purpose of these trials is to estimate the safety and effectiveness of gene therapies in human patients with specific genetic forms of epilepsy. It is an AAV-based gene therapy that has the potential to enhance the quality of life for people with drug-resistant focal epilepsy, for which no effective treatment is available currently. The therapy candidate CG01 uses a gene therapy vector to deliver a combination of neuropeptide Y and its receptor Y2 directly to the area of the brain that triggers epileptic seizures.

Thus, gene therapy is likely to serve as a promising new trend in the epilepsy market in the coming years.

Middle East & Africa Epilepsy Market Overview

The epilepsy market in the MEA is further segmented into the UAE, Saudi Arabia, South Africa, and the Rest of MEA. The median prevalence of epilepsy in MEA countries is 7 per 1,000 persons. The most common risk factors that were found to be associated with increased risk of epilepsy development include consanguinity, family history of epilepsy, and a history of perinatal infections.

Middle East & Africa Epilepsy Market Revenue and Forecast to 2030 (US$ Million)

Middle East & Africa Epilepsy Market Revenue and Forecast to 2030 (US$ Million)

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Middle East & Africa Epilepsy Market Segmentation

The Middle East & Africa epilepsy market is categorized into type, route of administration, treatment type, age group, distribution channel, and country.

Based on type, the Middle East & Africa epilepsy market is categorized into progressive myoclonic epilepsy, reflex epilepsy, generalized epilepsy, and other. The generalized epilepsy segment held the largest market share in 2022.

In terms of route of administration, the Middle East & Africa epilepsy market is categorized into oral, parenteral, and others. The oral segment held the largest market share in 2022.

By treatment type, the Middle East & Africa epilepsy market is segmented into first generation drugs, second generation drugs, and third generation drugs. The third-generation drugs segment held the largest market share in 2022.

Based on age group, the Middle East & Africa epilepsy market is bifurcated into adult and children. The adult segment held a larger market share in 2022.

In terms of distribution channel, the Middle East & Africa epilepsy market is categorized into hospital pharmacies, retail pharmacies, and others. The hospital pharmacies segment held the largest market share in 2022.

By country, the Middle East & Africa epilepsy market is segmented into Saudi Arabia, South Africa, the UAE, and the Rest of Middle East & Africa. The Rest of Middle East & Africa dominated the Middle East & Africa epilepsy market share in 2022.

Abbott Laboratories, Pfizer Inc, Eisai Co Ltd, UCB SA, LivaNova Plc, Novartis AG, Medtronic Plc, GSK Plc, and H. Lundbeck AS are some of the leading companies operating in the Middle East & Africa epilepsy market.

TABLE OF CONTENTS

 

1. Introduction

1.1 The Insight Partners Research Report Guidance

1.2 Market Segmentation

2. Executive Summary

2.1 Key Insights

2.2 Market Attractiveness

3. Research Methodology

3.1 Coverage

3.2 Secondary Research

3.3 Primary Research

4. Middle East & Africa Pipeline Studies for Epilepsy Therapy Approaches

4.1 Pipeline Studies for Epilepsy Therapy Approaches

4.1.1 Cell and Gene Therapy Approaches

4.1.2 Encapsulated cell bio delivery (ECB) system

4.1.3 Gene Therapy for Epilepsy Clinical Overview

4.1.3.1 Genetic Therapies Adopted for Clinic Research of Epilepsy

4.1.3.1.1 Gene Supplementation - Overview

4.1.3.1.2 Gene Modulation - Overview

4.1.3.1.3 Antisense Oligonucleotides and RNA Interference - Overview

4.1.3.1.4 Neuropeptides - Overview

4.1.3.1.5 Engineered Channels - Overview

4.1.3.1.6 Endogenous Channels - Overview

4.1.3.2 Pipeline Studies of Viral Vectors for Epilepsy

4.1.3.3 Pipeline Studies of Non-Viral Vectors for Epilepsy

4.1.3.3.1 Polymer-based Non-Viral Vectors for Epilepsy

4.1.3.3.2 Lipid-based Non-Viral Vectors for Epilepsy

4.1.3.4 Adeno-Associated Virus (AAV)-Mediated Neuromodulatory Peptides - Overview

4.1.3.5 Neurotrophic Factors for Gene Therapy Approaches

4.1.3.6 Potassium Channels For Human Epileptic Phenotypes

4.1.3.7 Enzyme Inducing Antiepileptic Drugs

5. Middle East & Africa Epilepsy Market - Key Market Dynamics

5.1 Market Drivers

5.1.1 Rising Prevalence of Epilepsy

5.1.2 Increasing Investments in Development of Epilepsy Therapies

5.2 Market Restraints

5.2.1 Recall of Products

5.3 Market Opportunities

5.3.1 Surge in Awareness Programs Conducted by Organizations

5.4 Future Trends

5.4.1 Gene Therapy as Promising Treatment Approach

5.5 Impact of Drivers and Restraints:

6. Epilepsy Market - Middle East & Africa Analysis

6.1 Middle East & Africa: Epilepsy Market

7. Middle East & Africa Epilepsy Market Analysis - by Type

7.1 Overview

7.2 Progressive Myoclonic Epilepsy

7.2.1 Overview

7.2.2 Progressive Myoclonic Epilepsy: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

7.3 Reflex Epilepsy

7.3.1 Overview

7.3.2 Reflex Epilepsy: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

7.4 Generalized Epilepsy

7.4.1 Overview

7.4.2 Generalized Epilepsy: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

7.5 Other

7.5.1 Overview

7.5.2 Other: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

8. Middle East & Africa Epilepsy Market Analysis - by Route of Administration

8.1 Overview

8.2 Oral

8.2.1 Overview

8.2.2 Oral: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

8.3 Parenteral

8.3.1 Overview

8.3.2 Parenteral: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

8.4 Others

8.4.1 Overview

8.4.2 Others: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

9. Middle East & Africa Epilepsy Market Analysis - by Treatment Type

9.1 Overview

9.2 First Generation Drugs

9.2.1 Overview

9.2.2 First Generation Drugs: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

9.3 Second Generation Drugs

9.3.1 Overview

9.3.2 Second Generation Drugs: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

9.4 Third Generation Drugs

9.4.1 Overview

9.4.2 Third Generation Drugs: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

10. Middle East & Africa Epilepsy Market Analysis - by Age Group

10.1 Overview

10.2 Adult

10.2.1 Overview

10.2.2 Adult: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

10.3 Children

10.3.1 Overview

10.3.2 Children: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

11. Middle East & Africa Epilepsy Market Analysis - by Distribution Channel

11.1 Overview

11.2 Hospital Pharmacies

11.2.1 Overview

11.2.2 Hospital Pharmacies: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

11.3 Retail Pharmacies

11.3.1 Overview

11.3.2 Retail Pharmacies: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

11.4 Others

11.4.1 Overview

11.4.2 Others: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

12. Middle East & Africa Epilepsy Market - Country Analysis

12.1 Middle East & Africa Epilepsy Market Overview

12.1.1 Middle East & Africa: Epilepsy Market Breakdown, by Key Country, 2022 and 2030 (%)

12.1.1.1 Saudi Arabia: Epilepsy Market Overview

12.1.1.2 Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

12.1.1.2.1 Saudi Arabia: Epilepsy Market Breakdown, by Type

12.1.1.2.2 Saudi Arabia: Epilepsy Market Breakdown, by Route of Administration

12.1.1.2.3 Saudi Arabia: Epilepsy Market Breakdown, by Treatment Type

12.1.1.2.4 Saudi Arabia: Epilepsy Market Breakdown, by Age Group

12.1.1.2.5 Saudi Arabia: Epilepsy Market Breakdown, by Distribution Channel

12.1.1.3 South Africa: Epilepsy Market Overview

12.1.1.4 South Africa: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

12.1.1.4.1 South Africa: Epilepsy Market Breakdown, by Type

12.1.1.4.2 South Africa: Epilepsy Market Breakdown, by Route of Administration

12.1.1.4.3 South Africa: Epilepsy Market Breakdown, by Treatment Type

12.1.1.4.4 South Africa: Epilepsy Market Breakdown, by Age Group

12.1.1.4.5 South Africa: Epilepsy Market Breakdown, by Distribution Channel

12.1.1.5 United Arab Emirates: Epilepsy Market Overview

12.1.1.6 United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

12.1.1.6.1 United Arab Emirates: Epilepsy Market Breakdown, by Type

12.1.1.6.2 United Arab Emirates: Epilepsy Market Breakdown, by Route of Administration

12.1.1.6.3 United Arab Emirates: Epilepsy Market Breakdown, by Treatment Type

12.1.1.6.4 United Arab Emirates: Epilepsy Market Breakdown, by Age Group

12.1.1.6.5 United Arab Emirates: Epilepsy Market Breakdown, by Distribution Channel

12.1.1.7 Rest of Middle East & Africa: Epilepsy Market Overview

12.1.1.8 Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

12.1.1.8.1 Rest of Middle East & Africa: Epilepsy Market Breakdown, by Type

12.1.1.8.2 Rest of Middle East & Africa: Epilepsy Market Breakdown, by Route of Administration

12.1.1.8.3 Rest of Middle East & Africa: Epilepsy Market Breakdown, by Treatment Type

12.1.1.8.4 Rest of Middle East & Africa: Epilepsy Market Breakdown, by Age Group

12.1.1.8.5 Rest of Middle East & Africa: Epilepsy Market Breakdown, by Distribution Channel

13. Industry Landscape

13.1 Overview

13.2 Growth Strategies in Epilepsy Market

13.3 Organic Growth Strategies

13.3.1 Overview

13.4 Inorganic Growth Strategies

13.4.1 Overview

14. Company Profiles

14.1 Abbott Laboratories

14.1.1 Key Facts

14.1.2 Business Description

14.1.3 Products and Services

14.1.4 Financial Overview

14.1.5 SWOT Analysis

14.1.6 Key Developments

14.2 Pfizer Inc

14.2.1 Key Facts

14.2.2 Business Description

14.2.3 Products and Services

14.2.4 Financial Overview

14.2.5 SWOT Analysis

14.2.6 Key Developments

14.3 Eisai Co Ltd

14.3.1 Key Facts

14.3.2 Business Description

14.3.3 Products and Services

14.3.4 Financial Overview

14.3.5 SWOT Analysis

14.3.6 Key Developments

14.4 UCB SA

14.4.1 Key Facts

14.4.2 Business Description

14.4.3 Products and Services

14.4.4 Financial Overview

14.4.5 SWOT Analysis

14.4.6 Key Developments

14.5 LivaNova Plc

14.5.1 Key Facts

14.5.2 Business Description

14.5.3 Products and Services

14.5.4 Financial Overview

14.5.5 SWOT Analysis

14.5.6 Key Developments

14.6 Novartis AG

14.6.1 Key Facts

14.6.2 Business Description

14.6.3 Products and Services

14.6.4 Financial Overview

14.6.5 SWOT Analysis

14.6.6 Key Developments

14.7 Medtronic Plc

14.7.1 Key Facts

14.7.2 Business Description

14.7.3 Products and Services

14.7.4 Financial Overview

14.7.5 SWOT Analysis

14.7.6 Key Developments

14.8 GSK Plc

14.8.1 Key Facts

14.8.2 Business Description

14.8.3 Products and Services

14.8.4 Financial Overview

14.8.5 SWOT Analysis

14.8.6 Key Developments

14.9 H. Lundbeck AS

14.9.1 Key Facts

14.9.2 Business Description

14.9.3 Products and Services

14.9.4 Financial Overview

14.9.5 SWOT Analysis

14.9.6 Key Developments

15. Appendix

15.1 About The Insight Partners

 

 

List of Tables

Table 1. Middle East & Africa Epilepsy Market Segmentation

Table 2. Cell Therapy Approach - An Overview

Table 3. Gene Therapy Approach - An Overview

Table 4. Encapsulated cell bio delivery (ECB) system Cell and Gene Therapy Approach - An Overview

Table 5. Preclinically Tested Genetic Therapies for Epilepsy

Table 6. Clinical Trials for Epilepsy Gene Therapy: Overview

Table 7. Viral Vectors Comparison with respect to Various Parameters

Table 8. Subfamilies of Human K+ Channels Involved in Epilepsies

Table 9. Enzyme-Inducing Antiepileptic Drugs

Table 10. Enzyme-Inducing Antiepileptic Drugs & Drug Target Types Overview

Table 11. Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Type

Table 12. Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Route of Administration

Table 13. Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Treatment Type

Table 14. Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Age Group

Table 15. Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Distribution Channel

Table 16. South Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Type

Table 17. South Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Route of Administration

Table 18. South Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Treatment Type

Table 19. South Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Age Group

Table 20. South Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Distribution Channel

Table 21. United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Type

Table 22. United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Route of Administration

Table 23. United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Treatment Type

Table 24. United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Age Group

Table 25. United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Distribution Channel

Table 26. Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Type

Table 27. Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Route of Administration

Table 28. Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Treatment Type

Table 29. Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Age Group

Table 30. Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million) - by Distribution Channel

Table 31. Recent Organic Growth Strategies in Epilepsy Market

Table 32. Recent Inorganic Growth Strategies in the Epilepsy Market

 

List of Figures

Figure 1. Middle East & Africa Epilepsy Market Segmentation, by Country

Figure 2. Epilepsy Market - Key Market Dynamics

Figure 3. Impact Analysis of Drivers and Restraints

Figure 4. Epilepsy Market Revenue (US$ Million), 2020-2030

Figure 5. Epilepsy Market Share (%) - by Type (2022 and 2030)

Figure 6. Progressive Myoclonic Epilepsy: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 7. Reflex Epilepsy: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 8. Generalized Epilepsy: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 9. Other: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 10. Epilepsy Market Share (%) - by Route of Administration (2022 and 2030)

Figure 11. Oral: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 12. Parenteral: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 13. Others: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 14. Epilepsy Market Share (%) - by Treatment Type (2022 and 2030)

Figure 15. First Generation Drugs: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 16. Second Generation Drugs: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 17. Third Generation Drugs: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 18. Epilepsy Market Share (%) - by Age Group (2022 and 2030)

Figure 19. Adult: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 20. Children: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 21. Epilepsy Market Share (%) - by Distribution Channel (2022 and 2030)

Figure 22. Hospital Pharmacies: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 23. Retail Pharmacies: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 24. Others: Epilepsy Market - Revenue and Forecast to 2030 (US$ Million)

Figure 25. Middle East & Africa: Epilepsy Market, by Key Country - Revenue (2022) (US$ Million)

Figure 26. Middle East & Africa: Epilepsy Market Breakdown, by Key Countries, 2022 and 2030 (%)

Figure 27. Saudi Arabia: Epilepsy Market - Revenue and Forecast to 2030(US$ Million)

Figure 28. South Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million)

Figure 29. United Arab Emirates: Epilepsy Market - Revenue and Forecast to 2030(US$ Million)

Figure 30. Rest of Middle East & Africa: Epilepsy Market - Revenue and Forecast to 2030(US$ Million)

Figure 31. Growth Strategies in Epilepsy Market

 

 

 

  1. Abbott Laboratories
  2. Pfizer Inc
  3. Eisai Co Ltd
  4. UCB SA
  5. LivaNova Plc
  6. Novartis AG
  7. Medtronic Plc
  8. GSK Plc
  9. H. Lundbeck AS
  • Save and reduce time carrying out entry-level research by identifying the growth, size, leading players, and segments in the Middle East & Africa epilepsy market.
  • Highlights key business priorities in order to assist companies to realign their business strategies.
  • The key findings and recommendations highlight crucial progressive industry trends in the Middle East & Africa epilepsy market, thereby allowing players across the value chain to develop effective long-term strategies.
  • Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
  • Scrutinize in-depth Middle East & Africa market trends and outlook coupled with the factors driving the Middle East & Africa epilepsy market, as well as those hindering it.
  • Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to client products, segmentation, pricing, and distribution.
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