Europe Organoids Market Report (2021-2031) by Scope, Segmentation, Dynamics, and Competitive Analysis

The Europe organoids market size is expected to reach US$ 5,016.03 million by 2031 from US$ 1,018.12 million in 2023. The market is estimated to record a CAGR of 22.1% from 2023 to 2031.

Executive Summary and Europe Organoids Market Analysis:

The Europe organoids market is segmented into Germany, France, Italy, the UK, Spain, and the Rest of Europe. The market growth is associated with the rising demand for tissue engineering and organ transplantation; increasing adoption of organoids for disease modeling, gene mutation, and tumor modeling; and growing research activities associated with organoids. In addition, increased funding and public-private investments are expected to create lucrative opportunities for the market growth in the coming years in the region.

Europe Organoids Market Strategic Insights

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Europe Organoids Market Segmentation Analysis

Key segments that contributed to the derivation of the Europe organoids market analysis are type, application, source, offering, and method.

• Based on type, the Europe organoids market is segmented into intestine, liver, stomach, pancreas, lung, brain, kidney, and others. The intestine held the largest share of the market in 2023.
• Based on application, the Europe organoids market is segmented into developmental biology disease, pathology of infectious disease, regenerative medicine, drug toxicity and efficacy testing, drug discovery and personalized medicine, and others. The developmental biology disease held the largest share of the market in 2023.
• Based on source, the Europe organoids market is bifurcated into pluripotent stem cells and organ-specific adult stem cell. The pluripotent stem cells held a larger share of the market in 2023.
• Based on offering, the Europe organoids market is segmented into instruments, consumables, and services. The consumables held the largest share of the market in 2023. The instruments segment is further subsegmented into devices and equipment. The consumables segment is further subsegmented into sensors and others.
• Based on method, the Europe organoids market is segmented into micropatterned plates, ultralow attachment plates, hanging drop, microdroplet or emulsion, and others. The hanging drop held the largest share of the market in 2023.

Europe Organoids Market Outlook

The increasing demand for new and advanced drugs is driving the overall pace of drug discovery and research. According to ClinicalTrials.gov, the total number of clinical trial studies in 2021 was estimated at 384,288. A recent survey by the HUB states that organoids can potentially make expensive drugs more cost-effective by identifying patients who are not likely to benefit from the drug and omitting them from clinical trials. An increasing number of clinical trials worldwide is expected to drive the demand for advanced medical technologies, including organoid models. Organoids in drug discovery are not limited to just cancer; they are also used in other disease studies, including cystic fibrosis, polycystic kidney disease, microcephaly, and gut and airway infections. For instance, organoids can summarize the properties of an organ, such as organ structure and function. They can also restore the original genetic and epigenetic state of a tissue or an organ, making them suitable for gene editing.

Various studies have shown positive results of combining CRISPR-Cas9 technology with organoids, which has led to breakthroughs in cystic fibrosis treatment. According to the study "CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank," published in 2020, a biobank of cystic fibrosis intestinal organoids represented 664 patients, and ~20% of them were theoretically able to efficiently repair nonsense mutations in the cystic fibrosis transmembrane conductor receptor through adenine base editors. Despite a few achievements of gene-edited organoids in some animal models, their efficiency is significantly low, and the success rate is not optimal. Therefore, R&D regarding the safety, long-term stability, and functionality of gene-edited organoids becomes crucial. Thus, the continued focus on drug discovery activities to tap the untapped areas of medicine offers more significant growth opportunities for the organoids market.

Europe Organoids Market Country Insights

Based on country, the Europe organoids market comprises Germany, France, the UK, Italy, Spain, and the Rest of Europe. Germany held the largest share in 2023.

Germany is one of the leading nations for biotechnology-related markets due to the high quality of its finished products and the presence of biotechnology giants that ensure the attainment of the optimum efficacy and quality of drugs and medicines. For instance, in November 2020, a team of scientists at the Max Planck Institute for Molecular Biomedicine in Münster, Germany, successfully used human cells to produce midbrain organoids in a fully automated process. The team made significant advancements in organoid generation and analysis, which made their discoveries suitable for implementation into large-scale research such as high-throughput drug discovery.

The growing demand for tissue engineering and organ transplantation in Germany is expected to boost the market growth in the coming years. There is a huge demand for organs, and the disparity is excessive as there is less organ donation. According to the German Reference Centre for Ethics in the Life Sciences (DRZE), 2,905 organs were donated in 2021, and the organ demand on the transplant list was 8,730. Also, most field scientists currently use human organoids to study human disease, but these tissues can act as organ transplants. However, using human organoids in transplants avoids the fundamental problems of tissue rejection and the possible introduction of animal pathogens or oncogenes into human recipients. Therefore, the increased development of organoids is required to use organoids for organ transplantations.

Europe Organoids Market Report Highlights

Europe Organoids Market Company Profiles

Some of the key players operating in the market STEMCELL Technologies Inc; Molecular Devices, LLC.; Hubrecht Organoid Technology; Definigen; Organoid Therapeutics; Thermo Fisher Scientific Inc; Corning Inc; Merck KGaA; InSphero; ACRO Biosystems; Bio-Techne Corp; SUN bioscience SA; ORGANOID SCIENCES Co., Ltd.; Crown Bioscience Inc; Sartorius AG; 3D Biotek LLC; Prellis Biologics Inc.; 3Dnamics Inc.; and Cellesce Ltd, among others. These players are adopting various strategies such as expansion, product innovation, and mergers and acquisitions to provide innovative products to their consumers and increase their market share.

Europe Organoids Market Research Methodology :

The following methodology has been followed for the collection and analysis of data presented in this report:

• Secondary Research

The research process begins with comprehensive secondary research, utilizing both internal and external sources to gather qualitative and quantitative data for each market. Commonly referenced secondary research sources include, but are not limited to:

• Company websites, annual reports, financial statements, broker analyses, and investor presentations.
• Industry trade journals and other relevant publications.
• Government documents, statistical databases, and market reports.
• News articles, press releases, and webcasts specific to companies operating in the market.

Note: All financial data included in the Company Profiles section has been standardized to USD. For companies reporting in other currencies, figures have been converted to USD using the relevant exchange rates for the corresponding year.

• Primary Research

The Insight Partners conducts a significant number of primary interviews each year with industry stakeholders and experts to validate its data analysis, and gain valuable insights. These research interviews are designed to:

• Validate and refine findings from secondary research.
• Enhance the expertise and market understanding of the analysis team.
• Gain insights into market size, trends, growth patterns, competitive dynamics, and future prospects.

Primary research is conducted via email interactions and telephone interviews, encompassing various markets, categories, segments, and sub-segments across different regions. Participants typically include:

• Industry stakeholders: Vice Presidents, business development managers, market intelligence managers, and national sales managers
• External experts: Valuation specialists, research analysts, and key opinion leaders with industry-specific expertise

Europe Organoids Market Country and Regional Insights