Previsioni di mercato della diagnostica per il cancro al cervello in Sud e Centro America fino al 2028 – Impatto del COVID-19 e analisi regionale per tipo diagnostico (test di imaging, puntura lombare, biopsia, test molecolari e altri); Tipo di cancro (neuroma acustico, astrocitoma, craniofaringiomi, ganglioneuromi, glioblastoma multiforme, meningiomi, ependimomi e altri); Utente finale (ospedali, cliniche specialistiche, centri chirurgici ambulatoriali e altri)

TIPRE00025906 | Pages: 145 | Medical Device | Nov 2021 | Type: Regional | Status: Published

Introduzione al mercato

I tumori al cervello sono causati dalla crescita extracellulare delle cellule nel cervello che causano i tumori. Il tumore comprende tumori cerebrali primari e tumori cerebrali secondari. I tumori cerebrali primari si formano nel cervello e non si diffondono ad altre parti del corpo, mentre i tumori secondari, noti anche come metastasi, sono quei tumori che hanno avuto inizio in un\'altra parte del corpo. I tumori al cervello sono classificati in 40 tipi principali, ulteriormente classificati in due gruppi principali: benigni, ovvero a crescita lenta e con minore possibilità di diffusione, e maligni, ovvero cancerosi e con maggiore probabilità di diffusione.

< p>Pertanto, si prevede che l\'aumento della prevalenza del cancro al cervello creerà una domanda significativa per la diagnostica del cancro al cervello nei prossimi anni, che si prevede guiderà ulteriormente il mercato della diagnostica del cancro al cervello.

Il COVID? La pandemia del 19 rappresenta un test critico per i sistemi sanitari pubblici già sovraccarichi e sottofinanziati del Sud e Centro America. Soffre di gravi disuguaglianze. Con una vasta popolazione che vive in povertà, l’America centrale e meridionale deve far fronte continuamente a diffusi problemi sanitari dovuti al sovraffollamento, ai servizi igienico-sanitari limitati, all’insicurezza alimentare e alle condizioni ambientali imprevedibili. Gli ospedali statali, sottofinanziati, sono l\'unica fonte di assistenza medica nella regione. Il Brasile si trova in una situazione critica a causa del COVID-1. La mancanza di risorse sta creando ulteriori sfide nella regione, ostacolando la crescita del mercato della diagnostica del cancro al cervello. Tutti questi fattori limiteranno la distribuzione e l’adozione di prodotti e servizi diagnostici che limiteranno la crescita del mercato. Tuttavia, man mano che la vaccinazione continua in questi paesi, i vari attori del mercato in questa regione ricominceranno a concentrarsi sullo sviluppo della diagnostica del cancro al cervello e ad aumentare la distribuzione dei prodotti. Pertanto l\'impatto della pandemia sarà moderato sul mercato della diagnostica del cancro al cervello.

 

Panoramica e dinamiche del mercato

Si prevede che il mercato della diagnostica del cancro al cervello nell\'America meridionale e centrale crescerà da 69,7 milioni di dollari nel 2021 a 175,8 milioni di dollari entro il 2028; si stima che crescerà a un CAGR del 14,1% dal 2021 al 2028. Il termine \"tumore cerebrale primario\" si riferisce a un tumore che inizia nel cervello. Il cancro del cervello e del sistema nervoso è la decima causa di mortalità negli uomini e nelle donne. Nel corso della vita di una persona, le probabilità di avere questa forma di tumore sono inferiori all\'1%. La maggior parte dei tumori maligni primari del sistema nervoso centrale (SNC) sono tumori cerebrali, che rappresentano dall’85% al 90% di tutti i casi. I tumori al cervello possono essere fatali, avere un grave impatto sulla qualità della vita e, in definitiva, trasformare la vita di un paziente e della sua famiglia. Inoltre, la diagnosi precoce dei tumori offre spesso più opzioni terapeutiche. La tecnologia di imaging avanzata può individuare la posizione dei tumori al cervello. Gli strumenti diagnostici includono la risonanza magnetica (MRI) e la tomografia computerizzata (TC o TAC). La risonanza magnetica intraoperatoria può essere utilizzata anche per guidare la biopsia tissutale e la resezione del tumore durante l\'intervento chirurgico. La spettroscopia di risonanza magnetica (MRS) viene utilizzata per esaminare le caratteristiche chimiche dei tumori. Pertanto, l’aumento della prevalenza del cancro al cervello richiede fortemente strumenti diagnostici per il cancro al cervello.      

 

Segmenti chiave del mercato

In termini di tipo diagnostico, il segmento dei test di imaging rappresentava la quota maggiore del mercato della diagnostica del cancro al cervello dell’America meridionale e centrale nel 2020. In termini di tipo di cancro, il segmento del glioblastoma multiforme rappresentava la quota maggiore del mercato della diagnostica del cancro al cervello dell’America meridionale e centrale. mercato della diagnostica per il cancro al cervello nel 2020. In termini di utenti finali, il segmento ospedaliero ha rappresentato la quota maggiore del mercato della diagnostica per il cancro al cervello dell\'America centrale e meridionale nel 2020.

Principali fonti e aziende elencate

Alcune principali fonti primarie e secondarie a cui si fa riferimento per la preparazione Questo rapporto sul mercato della diagnostica del cancro al cervello in Sud e Centro America comprende siti Web aziendali, relazioni annuali, rapporti finanziari, documenti governativi nazionali e database statistici, tra gli altri. Le principali aziende elencate nel rapporto sono Thermo Fisher Scientific Inc., Siemens Healthineers A, GE Healthcare, Biocept, Inc., Koninklijke Philips NV, Canon Medical Systems, Hitachi, Ltd. e Neusoft Medical Systems.

 

Motivi per acquistare il rapporto

  • Comprendere il panorama del mercato della diagnostica per il cancro al cervello dell\'America meridionale e centrale e identificare i segmenti di mercato che hanno maggiori probabilità di garantire un forte ritorno
  • Mantenere un vantaggio comprendendo il panorama competitivo in continua evoluzione per il mercato della diagnostica del cancro al cervello del Sud e Centro America
  • Pianificare in modo efficiente fusioni e acquisizioni e accordi di partnership nel Sud e America Centrale del mercato della diagnostica del cancro al cervello identificando i segmenti di mercato con le vendite probabili più promettenti
  • Aiuta a prendere decisioni aziendali consapevoli attraverso un\'analisi percettiva e completa delle prestazioni del mercato di vari segmenti del mercato della diagnostica del cancro al cervello del Sud e Centro America
  • Ottenere previsioni sui ricavi di mercato per vari segmenti dal 2021 al 2028 nella regione dell\'America meridionale e centrale.

 

Segmentazione del mercato della diagnostica per il cancro al cervello dell\'America meridionale e centrale

 

Per tipo diagnostico

  • Test di imaging
    • MRI
    • TAC
    • PET
  • Biopsia
  • Test molecolari
  • Puntura lombare
  • Altri

 

Per tipo di cancro

< ul>
  • Glioblastoma multiforme
  • Astrocitomi
  • Ependimomi
  • Altri
  •  

    Da Utente finale

    • Ospedali
    • Cliniche specializzate
    • Centri chirurgici ambulatoriali
    • Altri

    Per Paese

    • America centrale e meridionale
      • Brasile
      • Argentina
      • Resto dell\'America centrale e meridionale

     

    Aziende citate

    1. Thermo Fisher Scientific Inc.
    2. Siemens Healthineers A
    3. GE Healthcare
    4. Biocept, Inc.
    5. Koninklijke Philips NV
    6. Canon Medical Systems
    7. Hitachi, Ltd.
    8. Neusoft Medical Systems

     

     

    TABLE OF CONTENTS

    1.           Introduction

    1.1          Scope of the Study

    1.2          The Insight Partners Research Report Guidance

    1.3          Market Segmentation

    1.3.1          Brain Cancer Diagnostics Market – By Diagnostic Type

    1.3.2          Brain Cancer Diagnostics Market – By Cancer Type

    1.3.3          Brain Cancer Diagnostics Market – By End User

    1.3.4          South and Central America Brain Cancer Diagnostics Market – By Country

    2.           South and Central America Brain Cancer Diagnostics Market – Key Takeaways

    3.           Research Methodology

    3.1          Coverage

    3.2          Secondary Research

    3.3          Primary Research

    4.           South and Central America Brain Cancer Diagnostics Market – Market Landscape

    4.1          Overview

    4.2          PEST Analysis

    4.2.1          Brain Cancer Diagnostics Market- South and Central America PEST Analysis

    4.3          Expert Opinion

    5.           South and Central America Brain Cancer Diagnostics Market - Key Market Dynamics

    5.1          Market Drivers

    5.1.1          Increase in Prevalence of Brain Cancer

    5.1.2          Rise in Number of Cigarette Smokers

    5.2          Market Restraints

    5.2.1          High Cost of Diagnosis

    5.3          Future Trends

    5.3.1          Use of Stimulated Raman Histology (SRH)?Artificial Intelligence (AI) to Enhance Brain Tumor Diagnosis During Surgery

    5.4          Impact Analysis

    6.           Brain Cancer Diagnostics Market – South and Central America Analysis

    6.1          South and Central America Brain Cancer Diagnostics Market Revenue Forecasts and Analysis

    7.           South and Central America Brain Cancer Diagnostics Market Analysis and Forecasts To 2028 – By Diagnostic Type

    7.1          Overview

    7.2          Brain Cancer Diagnostics Market Revenue Share, by Diagnostic Type (2020 and 2028)

    7.3          Imaging Tests

    7.3.1          Overview

    7.3.2          Imaging Tests: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.3.3          MRI

    7.3.3.1             Overview

    7.3.3.2             MRI: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.3.4          CT Scan

    7.3.4.1             Overview

    7.3.4.2             CT Scan: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.3.5          Positron emission tomography (PET)

    7.3.5.1             Overview

    7.3.5.2             Positron emission tomography (PET): Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.4          Lumbar Puncture

    7.4.1          Overview

    7.4.2          Lumbar Puncture: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.5          Biopsy

    7.5.1          Overview

    7.5.2          Biopsy: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.6          Molecular Testing

    7.6.1          Overview

    7.6.2          Molecular Testing: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    7.7          Others

    7.7.1          Overview

    7.7.2          Others: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    8.           South and Central America Brain Cancer Diagnostics Market Analysis and Forecasts To 2028 – By Cancer Type

    8.1          Overview

    8.2          Brain Cancer Diagnostics Market Revenue Share, by Cancer Type (2020 and 2028)

    8.3          Astrocytomas

    8.3.1          Overview

    8.3.2          Astrocytomas: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    8.4          Glioblastoma Multiforme

    8.4.1          Overview

    8.4.2          Glioblastoma Multiforme: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    8.5          Ependymomas

    8.5.1          Overview

    8.5.2          Ependymomas: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    8.6          Others

    8.6.1          Overview

    8.6.2          Others: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    9.           Brain Cancer Diagnostics Market Analysis – By End user

    9.1          Overview

    9.2          Brain Cancer Diagnostics Market Revenue Share, by End User (2020 and 2028)

    9.3          Hospitals

    9.3.1          Overview

    9.3.2          Hospitals: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    9.4          Specialty Clinics

    9.4.1          Overview

    9.4.2          Specialty Clinics: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    9.5          Ambulatory Surgical Centers

    9.5.1          Overview

    9.5.2          Ambulatory Surgical Centers: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    9.6          Others

    9.6.1          Overview

    9.6.2          Others: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    10.        Brain Cancer Diagnostics Market Revenue and Forecasts to 2028 – Geographical Analysis

    10.1        South and Central America: Brain Cancer Diagnostics Market

    10.1.1        Overview

    10.1.2        South and Central America: Brain Cancer Diagnostics Market, by Country, 2021 & 2028 (%)

    10.1.2.1          Brazil: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    10.1.2.2          Brazil: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    10.1.2.2.1           Brazil Brain Cancer Diagnostics Market, by Diagnostics Type– Revenue and Forecast to 2028 (USD Million)

    10.1.2.2.1.1     Brazil Brain Cancer Diagnostics Market, by Imaging Test – Revenue and Forecast to 2028 (USD Million)

    10.1.2.2.2           Brazil Brain Cancer Diagnostics Market, by Cancer Type – Revenue and Forecast to 2028 (USD Million)

    10.1.2.2.3           Brazil Brain Cancer Diagnostics Market, by End User– Revenue and Forecast to 2028 (USD Million)

    10.1.2.3          Argentina: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    10.1.2.3.1           Argentina: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    10.1.2.3.2           Argentina Brain Cancer Diagnostics Market, by Diagnostics Type– Revenue and Forecast to 2028 (USD Million)

    10.1.2.3.2.1     Argentina Brain Cancer Diagnostics Market, by Imaging Test – Revenue and Forecast to 2028 (USD Million)

    10.1.2.3.3           Argentina Brain Cancer Diagnostics Market, by Cancer Type – Revenue and Forecast to 2028 (USD Million)

    10.1.2.3.4           Argentina Brain Cancer Diagnostics Market, by End User– Revenue and Forecast to 2028 (USD Million)

    10.1.2.4          Rest of South and Central America: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    10.1.2.4.1           Rest of South and Central America: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    10.1.2.4.2           Rest of South and Central America Brain Cancer Diagnostics Market, by Diagnostics Type– Revenue and Forecast to 2028 (USD Million)

    10.1.2.4.3           Rest of South and Central America Brain Cancer Diagnostics Market, by Imaging Test – Revenue and Forecast to 2028 (USD Million)

    10.1.2.4.4           Rest of South and Central America Brain Cancer Diagnostics Market, by Cancer Type– Revenue and Forecast to 2028 (USD Million)

    10.1.2.4.5           Rest of South and Central America Brain Cancer Diagnostics Market, by End User– Revenue and Forecast to 2028 (USD Million)

    11.        Impact Of COVID-19 Pandemic on South and Central America Brain Cancer Diagnostics Market

    11.1        South and Central America: Impact Assessment of COVID-19 Pandemic

    12.        Industry Landscape

    12.1        Overview

    12.2        Growth Strategies Done by the Companies in the Market, (%)

    12.1        Organic Developments

    12.1.1        Overview

    12.2        Inorganic Developments

    12.2.1        Overview

    13.        Company Profiles

    13.1        THERMO FISHER SCIENTIFIC INC.

    13.1.1        Key Facts

    13.1.2        Business Description

    13.1.3        Products and Services

    13.1.4        Financial Overview

    13.1.5        SWOT Analysis

    13.1.6        Key Developments

    13.2        Siemens Healthineers AG

    13.2.1        Key Facts

    13.2.2        Business Description

    13.2.3        Products and Services

    13.2.4        Financial Overview

    13.2.5        SWOT Analysis

    13.2.6        Key Developments

    13.3        GE Healthcare

    13.3.1        Key Facts

    13.3.2        Business Description

    13.3.3        Products and Services

    13.3.4        Financial Overview

    13.3.5        SWOT Analysis

    13.3.6        Key Developments

    13.4        Biocept, Inc.

    13.4.1        Key Facts

    13.4.2        Business Description

    13.4.3        Products and Services

    13.4.4        Financial Overview

    13.4.5        SWOT Analysis

    13.4.6        Key Developments

    13.5        Koninklijke Philips N.V.

    13.5.1        Key Facts

    13.5.2        Business Description

    13.5.3        Products and Services

    13.5.4        Financial Overview

    13.5.5        SWOT Analysis

    13.5.6        Key Developments

    13.6        Canon Medical Systems

    13.6.1        Key Facts

    13.6.2        Business Description

    13.6.3        Products and Services

    13.6.4        Financial Overview

    13.6.5        SWOT Analysis

    13.6.6        Key Developments

    13.7        Hitachi, Ltd.

    13.7.1        Key Facts

    13.7.2        Business Description

    13.7.3        Products and Services

    13.7.4        Financial Overview

    13.7.5        SWOT Analysis

    13.7.6        Key Developments

    13.8        Neusoft Medical Systems

    13.8.1        Key Facts

    13.8.2        Business Description

    13.8.3        Products and Services

    13.8.4        Financial Overview

    13.8.5        SWOT Analysis

    13.8.6        Key Developments

    14.        Appendix

    14.1        About the Insight Partners

    14.2        Glossary of Terms

     


    LIST OF TABLES

    Table 1.              Brazil Brain Cancer Diagnostics Market, by Diagnostics Type – Revenue and Forecast to 2028 (USD Million)

    Table 2.              Brazil Brain Cancer Diagnostics Market, by Imaging Test – Revenue and Forecast to 2028 (USD Million)

    Table 3.              Brazil Brain Cancer Diagnostics Market, by Cancer Type – Revenue and Forecast to 2028 (USD Million)

    Table 4.              Brazil Brain Cancer Diagnostics Market, by End User– Revenue and Forecast to 2028 (USD Million)

    Table 5.              Argentina Brain Cancer Diagnostics Market, by Diagnostics Type – Revenue and Forecast to 2028 (USD Million)

    Table 6.              Argentina Brain Cancer Diagnostics Market, by Imaging Test – Revenue and Forecast to 2028 (USD Million)

    Table 7.              Argentina Brain Cancer Diagnostics Market, by Cancer Type – Revenue and Forecast to 2028 (USD Million)

    Table 8.              Argentina Brain Cancer Diagnostics Market, by End User– Revenue and Forecast to 2028 (USD Million)

    Table 9.              Rest of South and Central America Brain Cancer Diagnostics Market, by Diagnostics Type – Revenue and Forecast to 2028  (USD Million)

    Table 10.            Rest of South and Central America Brain Cancer Diagnostics Market, by Imaging Test – Revenue and Forecast to 2028 (USD Million)

    Table 11.            Rest of South and Central America Brain Cancer Diagnostics Market, by Cancer Type – Revenue and Forecast to 2028 (USD Million)

    Table 12.            Rest of South and Central America Brain Cancer Diagnostics Market, by End User– Revenue and Forecast to 2028 (USD Million)

    Table 13.            Organic Developments in the Brain Cancer Diagnostics Market

    Table 14.            Inorganic Developments in the Brain Cancer Diagnostics Market

    Table 15.            Glossary of Terms, Brain Cancer Diagnostics Market

     


    LIST OF FIGURES

    Figure 1.            Brain Cancer Diagnostics Market Segmentation

    Figure 2.            South and Central America Brain Cancer Diagnostics Market Overview

    Figure 3.            Imaging Test Segment Held Largest Share of Diagnostic Type in Brain Cancer Diagnostics Market

    Figure 4.            Brazil is Expected to Show Remarkable Growth During the Forecast Period

    Figure 5.            Brain Cancer Diagnostics Market - South and Central America PEST Analysis

    Figure 6.            Brain Cancer Diagnostics Market Impact Analysis of Driver and Restraints

    Figure 7.            South and Central America Brain cancer diagnostics Market – Revenue Forecasts and Analysis – 2020- 2028

    Figure 8.            Brain Cancer Diagnostics Market Revenue Share, by Diagnostic Type (2020 and 2028)

    Figure 9.            Imaging Tests: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 10.          MRI: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 11.          CT Scan: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 12.          Positron emission tomography (PET): Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 13.          Lumbar Puncture: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 14.          Biopsy: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 15.          Molecular Testing: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 16.          Others: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 17.          Brain Cancer Diagnostics Market Revenue Share, by Cancer Type (2020 and 2028)

    Figure 18.          Astrocytomas: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 19.          Glioblastoma Multiforme: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 20.          Ependymomas: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 21.          Others: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 22.          Brain Cancer Diagnostics Market Revenue Share, by End User (2020 and 2028)

    Figure 23.          Hospitals: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 24.          Specialty Clinics: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 25.          Ambulatory Surgical Centers: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 26.          Others: Brain Cancer Diagnostics Market – Revenue and Forecast to 2028 (US$ Million)

    Figure 27.          South and Central America: Brain Cancer Diagnostics Market, by Key Country – Revenue (2021) (USD Million)

    Figure 28.          South and Central America: Brain Cancer Diagnostics Market, by Country, 2021 & 2028 (%)

    Figure 29.          Brazil: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    Figure 30.          Argentina: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    Figure 31.          Rest of South and Central America: Brain Cancer Diagnostics Market– Revenue and Forecast to 2028 (USD Million)

    Figure 32.          Impact of COVID-19 Pandemic in South and Central American Country Markets

    Figure 33.          Growth Strategies Done by the Companies in the Market, (%)

    1. Thermo Fisher Scientific Inc.
    2. Siemens Healthineers A
    3. GE Healthcare
    4. Biocept, Inc.
    5. Koninklijke Philips N.V
    6. Canon Medical Systems
    7. Hitachi, Ltd.
    8. Neusoft Medical Systems
    • Save and reduce time carrying out entry-level research by identifying the growth, size, leading players and segments in the South and Central America brain cancer diagnostics market.
    • Highlights key business priorities in order to assist companies to realign their business strategies
    • The key findings and recommendations highlight crucial progressive industry trends in the South and Central America brain cancer diagnostics market, thereby allowing players across the value chain to develop effective long-term strategies
    • Develop/modify business expansion plans by using substantial growth offering developed and emerging markets
    • Scrutinize in-depth South and Central America market trends and outlook coupled with the factors driving the brain cancer diagnostics market, as well as those hindering it
    • Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to client products, segmentation, pricing and distribution
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