Prévisions du marché européen des modèles de foie humain jusqu’en 2028 – Impact du COVID-19 et analyse régionale par type (organoïdes du foie, foie sur puce, modèles 2D, bioimpression 3D et autres), application (découverte de médicaments, éducation et autres) et utilisateur final (entreprises pharmaceutiques et biotechnologiques, instituts de recherche et autres)

Le marché européen des modèles de foie humain devrait passer de 84 347,25 milliers de dollars US en 2021 à 1 87 244,81 milliers de dollars US d’ici 2028 ; on estime qu\'elle connaîtra une croissance à un TCAC de 12,1 % entre 2021 et 2028.\\n\\nLe Royaume-Uni, l\'Allemagne, la France, l\'Italie et l\'Espagne sont des économies majeures en Europe. L’accent croissant mis sur le développement d’alternatives aux modèles d’expérimentation animale devrait stimuler la croissance du marché. Il y a eu une augmentation du nombre d’animaux utilisés dans la recherche avec l’augmentation de la recherche et du développement dans l’industrie médicale. Ces animaux sont nécessaires en grand nombre lors des tests précliniques. La douleur, la détresse et la mort des animaux lors d’expériences scientifiques sont depuis longtemps un sujet de discussion. Plusieurs cas montrent que les modèles animaux ne peuvent pas toujours prédire la réponse de l\'organisme aux médicaments, en particulier lors des études de toxicologie des médicaments. En effet, le métabolisme des médicaments et des toxines chez l\'homme diffère considérablement de celui des animaux, ce qui rend presque impossible l\'étude expérimentale du métabolisme des médicaments. modèles tels que les espèces de rongeurs de laboratoire. Le domaine de la recherche alternative s\'est accéléré au cours des 30 dernières années. En outre, plusieurs réglementations ont été introduites ces dernières années qui restreignent l\'utilisation des animaux dans les activités de recherche dans la région. Des méthodes telles que les tests in vitro , des cultures cellulaires, des simulations informatiques et de nouvelles techniques d\'imagerie/analyse ont été proposées comme moyens alternatifs de tests de médicaments et de produits chimiques pour éviter une utilisation excessive des animaux. Des outils bioinformatiques, des cultures cellulaires in vitro, des criblages enzymatiques et des organismes modèles sont nécessaires pour intégrer divers modèles informatiques. L’utilisation de techniques analytiques modernes, de collecte de données et de méthodes statistiques pour analyser les résultats de protocoles alternatifs peut fournir des résultats fiables. De plus, ces méthodes prennent moins de temps et sont moins coûteuses, et nécessitent une main d’œuvre limitée. Avec l’avènement de la culture cellulaire tridimensionnelle (3D) pour fabriquer des organoïdes, des modèles d’organoïdes humains plus pertinents sont explorés pour fournir des tests de médicaments sûrs et efficaces, minimisant ainsi le besoin d’expérimentation animale. Il est nécessaire de développer des modèles de test alternatifs pouvant fournir un environnement aussi proche que possible du corps humain. Divers instituts participent au développement de méthodes alternatives pour le développement de médicaments et la recherche biomédicale. Étant donné que les modèles hépatiques peuvent servir d’alternative aux modèles animaux, l’accent actuel mis sur la réduction de l’utilisation des animaux dans la recherche devrait soutenir la croissance du marché européen des modèles hépatiques humains. \\nDans le cas du COVID-19, l\'Europe est fortement touchée, notamment la France et la Russie. L’épidémie actuelle de COVID-19 n’a pas pris au dépourvu la recherche financée par l’UE. Le MSCA de la Commission européenne soutient des chercheurs exceptionnels dans la recherche de solutions aux défis posés par le nouveau coronavirus COVID-19 et d\'autres maladies infectieuses. En outre, pour faciliter le lancement d’essais cliniques liés au COVID-19, les autorités ont autorisé des procédures d’autorisation accélérées pour l’évaluation initiale des demandes d’autorisation. Cependant, les vagues émergentes de COVID-19 ont des impacts mitigés sur le marché en raison de la fermeture des sites d’essais cliniques. Selon l\'analyse de Phesi de septembre 2020, les suspensions mondiales des sites d\'essais cliniques ont culminé en juin et, après une première baisse, ont de nouveau augmenté et ont eu un impact significatif sur les essais de phase 2 et 3. Avec une incertitude économique mondiale croissante dans tous les secteurs, 2021 devrait être une année difficile pour la plupart des organisations de développement clinique dans le monde. La recherche clinique est essentielle au développement de nouveaux traitements et à une meilleure compréhension de la maladie, et la COVID-19 présente de nombreux défis. Les gouvernements de la région prévoient une reprise sûre et durable des essais non-Covid. Depuis septembre 2020, les données du NIHR Clinical Research Network ont montré que les études non liées au COVID reprennent, avec 45 % des études ouvertes au recrutement. De plus, les organoïdes sont utilisés par les chercheurs du partenariat EuroStemCell. Par exemple, un groupe international de scientifiques, comprenant des chercheurs de l’Institut IMBA de biotechnologie moléculaire de l’Académie autrichienne des sciences, a ralenti l’infection par le SRAS-CoV-2 chez les organoïdes, démontrant l’effet bloquant potentiel d’un médicament déjà en cours d’essais cliniques. Les chercheurs mènent diverses recherches pour gérer l’épidémie de COVID-19. Ainsi, l\'augmentation des activités de recherche entraînera des opportunités vitales pour le marché.\\n\\nGrâce aux nouvelles fonctionnalités et technologies, les fournisseurs peuvent attirer de nouveaux clients et étendre leur présence sur les marchés émergents. Ce facteur est susceptible de stimuler le marché européen des modèles de foie humain. Le marché européen des modèles de foie humain devrait croître à un bon TCAC au cours de la période de prévision. \\n\\nChiffre d\'affaires et prévisions du marché des modèles de foie humain en Europe jusqu\'en 2028 (en milliers de dollars) \\n\\nSegmentation du marché des modèles de foie humain en Europe \\nMarché des modèles de foie humain en Europe par type\\n- Organoïdes du foie\\n- Foie sur puce \\n- Modèles 2D\\n- Bio-impression 3D\\n- Autres\\nMarché des modèles de foie humain en Europe par application\\n- Découverte de médicaments\\n- Éducation\\n- Autres\\nMarché des modèles de foie humain en Europe par utilisateur final\\n- Pharmaceutique et biotechnologie Entreprises\\n- Instituts de recherche \\n- Autres \\nMarché des modèles de foie humain en Europe, par pays\\n- Allemagne\\n- France\\n- Royaume-Uni\\n- Italie \\n- Espagne\\n- Reste de l\'Europe\\nModèles de foie humain en Europe Marché -Entreprises mentionnées \\n- BioIVT\\n- CELLINK\\n- CN Bio Innovations\\n- Cyprio\\n- Emulate, Inc.\\n- InSphero\\n- Kerafast\\n- Kirkstall\\n- MIMETAS BV\\n- THERMO FISHER SCIENTIFIQUE INC.\\n\\n

TABLE OF CONTENTS
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 Europe Human Liver Models Market By Type
1.3.2 Europe Human Liver Models Market By Application
1.3.3 Europe Human Liver Models Market By End User
1.3.4 Europe Human Liver Models Market By Country
2. Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Europe Human Liver Models Market Market Landscape
4.1 Overview
4.2 Europe PEST Analysis
4.3 Experts Opinion
5. Europe Human Liver Models Market Key Market Dynamics
5.1 Market Drivers
5.1.1 Surging Prevalence of Liver Diseases
5.1.2 Escalating Focus on Developing Alternatives for Animal Testing Models
5.2 Market Restraints
5.2.1 Overpriced Liver Models
5.3 Market Opportunities
5.3.1 Growing focus on Drug Discovery Activities
5.4 Future Trends
5.4.1 Increasing Technological Advancements in Organ Printing
5.1 Impact analysis
6. Human Liver Models Market Europe Analysis
6.1 Europe Human Liver Models Market Revenue Forecast and Analysis
7. Europe Human Liver Models Market Analysis By Type
7.1 Overview
7.2 Europe Human Liver Models Market Revenue Share, by Type (2021 and 2028)
7.3 Liver Organoids
7.3.1 Overview
7.3.2 Liver Organoids: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.4 Liver-on-a-chip
7.4.1 Overview
7.4.2 Liver-on-a-chip: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.5 2D Models
7.5.1 Overview
7.5.2 2D Models: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.6 3D Bioprinting
7.6.1 Overview
7.6.2 3D Bioprinting: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.7 Others
7.7.1 Overview
7.7.2 Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
8. Europe Human Liver Models Market Analysis By Application
8.1 Overview
8.2 Europe Human Liver Models Market Share, by Application, 2021 and 2028, (%)
8.3 Educational
8.3.1 Overview
8.3.2 Educational: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
8.4 Drug Discovery
8.4.1 Overview
8.4.2 Drug Discovery: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
8.5 Other
8.5.1 Overview
8.5.2 Other: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
9. Europe Human Liver Models Market Analysis By End User
9.1 Overview
9.2 Europe Human Liver Models Market Share, by End User, 2021 and 2028, (%)
9.3 Research Institutes
9.3.1 Overview
9.3.2 Research Institutes: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
9.4 Pharmaceutical and Biotechnology Companies
9.4.1 Overview
9.4.2 Pharmaceutical and Biotechnology Companies: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
9.5 Others
9.5.1 Overview
9.5.2 Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
10. Europe Human Liver Models Market Country Analysis
10.1 Europe: Human Liver Models Market
10.1.1 Overview
10.1.2 Europe: Human Liver Models Market, by Country, 2021 & 2028 (%)
10.1.2.1 Germany: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.1.1 Germany: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.1.2 Germany: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.1.3 Germany: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.1.4 Germany: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.2 France: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.2.1 France: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.2.2 France: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.2.3 France: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.2.4 France: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.3 UK: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.3.1 UK: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.3.2 UK: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.3.3 UK: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.3.4 UK: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.4 Spain: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.4.1 Spain: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.4.2 Spain: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.4.3 Spain: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.4.4 Spain: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.5 Italy: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.5.1 Italy: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.5.2 Italy: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.5.3 Italy: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.5.4 Italy: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.6 Rest of Europe: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.6.1 Rest of Europe: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.6.2 Rest of Europe: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.6.3 Rest of Europe: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
10.1.2.6.4 Rest of Europe: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
11. Impact Of COVID-19 Pandemic on Europe Human Liver Models Market
11.1 Europe: Impact Assessment Of COVID-19 Pandemic
12. Industry Landscape
12.1 Overview
12.2 Organic Developments
12.2.1 Overview
12.3 Inorganic Developments
12.3.1 Overview
13. Company Profiles
13.1 THERMO FISHER SCIENTIFIC INC.
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
13.2 Emulate, Inc.
13.2.1 Key Facts
13.2.2 Business Description
13.2.3 Products and Services
13.2.4 Financial Overview
13.2.5 SWOT Analysis
13.2.6 Key Developments
13.3 CN Bio Innovations
13.3.1 Key Facts
13.3.2 Business Description
13.3.3 Products and Services
13.3.4 Financial Overview
13.3.5 SWOT Analysis
13.3.6 Key Developments
13.4 MIMETAS BV
13.4.1 Key Facts
13.4.2 Business Description
13.4.3 Products and Services
13.4.4 Financial Overview
13.4.5 SWOT Analysis
13.4.6 Key Developments
13.5 InSphero
13.5.1 Key Facts
13.5.2 Business Description
13.5.3 Products and Services
13.5.4 Financial Overview
13.5.5 SWOT Analysis
13.5.6 Key Developments
13.6 BioIVT
13.6.1 Key Facts
13.6.2 Business Description
13.6.3 Products and Services
13.6.4 Financial Overview
13.6.5 SWOT Analysis
13.6.6 Key Developments
13.7 CELLINK
13.7.1 Key Facts
13.7.2 Business Description
13.7.3 Products and Services
13.7.4 Financial Overview
13.7.5 SWOT Analysis
13.7.6 Key Developments
13.8 Kerafast
13.8.1 Key Facts
13.8.2 Business Description
13.8.3 Products and Services
13.8.4 Financial Overview
13.8.5 SWOT Analysis
13.8.6 Key Developments
13.9 Cyprio
13.9.1 Key Facts
13.9.2 Business Description
13.9.3 Products and Services
13.9.4 Financial Overview
13.9.5 SWOT Analysis
13.9.6 Key Developments
13.10 Kirkstall
13.10.1 Key Facts
13.10.2 Business Description
13.10.3 Products and Services
13.10.4 Financial Overview
13.10.5 SWOT Analysis
13.10.6 Key Developments
14. Appendix
14.1 About The Insight Partners
14.2 Glossary of Terms

LIST OF TABLES
Table 1. Europe Human Liver Models Market, Revenue and Forecast, 20192028 (US$ Thousand)
Table 2. Germany: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
Table 3. Germany: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
Table 4. Germany: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
Table 5. France: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
Table 6. France: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
Table 7. France: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
Table 8. UK: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
Table 9. UK: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
Table 10. UK: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
Table 11. Spain: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
Table 12. Spain: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
Table 13. Spain: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
Table 14. Italy: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
Table 15. Italy: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
Table 16. Italy: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
Table 17. Rest of Europe: Human Liver Models Market, by Type Revenue and Forecast to 2028 (US$ Thousand)
Table 18. Rest of Europe: Human Liver Models Market, by Application Revenue and Forecast to 2028 (US$ Thousand)
Table 19. Rest of Europe: Human Liver Models Market, by End User Revenue and Forecast to 2028 (US$ Thousand)
Table 20. Organic Developments Done by Companies
Table 21. Inorganic Developments Done by Companies
Table 22. Glossary of Terms

LIST OF FIGURES
Figure 1. Europe Human Liver Models Market Segmentation
Figure 2. Europe Human Liver Models Market Segmentation, By Country
Figure 3. Europe Human Liver Models Market Overview
Figure 4. Liver Organoids Held the Largest Share in 2020
Figure 5. The UK to Show Significant Growth During Forecast Period
Figure 6. Europe and PEST Analysis
Figure 7. Europe Human Liver Models Market Impact Analysis of Drivers and Restraints
Figure 8. Europe Human Liver Models Market Revenue Forecast and Analysis
Figure 9. Europe Human Liver Models Market Revenue Share, by Type (2021 and 2028)
Figure 10. Europe Liver Organoids: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 11. Europe Liver-on-a-chip: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 12. Europe 2D Models: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 13. Europe 3D Bioprinting: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 14. Europe Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 15. Europe Human Liver Models Market Share, by Application, 2021 and 2028 (%)
Figure 16. Europe Educational: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 17. Europe Drug Discovery: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 18. Europe Other: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 19. Europe Human Liver Models Market Share, by End User, 2021 and 2028 (%)
Figure 20. Europe Research Institutes: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 21. Europe Pharmaceutical and Biotechnology Companies: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 22. Europe Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 23. Europe: Human Liver Models Market, by Key Country Revenue (2021) (USD Thousand)
Figure 24. Europe: Human Liver Models Market, by Country, 2021 & 2028 (%)
Figure 25. Germany: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
Figure 26. France: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
Figure 27. UK: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
Figure 28. Spain: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
Figure 29. Italy: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
Figure 30. Rest of Europe: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)
Figure 31. Impact of COVID-19 Pandemic in European Country Markets

1. BioIVT
2. CELLINK
3. CN Bio Innovations
4. Cyprio
5. Emulate, Inc.
6. InSphero
7. Kerafast
8. Kirkstall
9. MIMETAS BV
10. THERMO FISHER SCIENTIFIC INC.

- Save and reduce time carrying out entry-level research by identifying the growth, size, leading players, and segments in the Europe human liver models market. - Highlights key business priorities in order to assist companies to realign their business strategies - The key findings and recommendations highlight crucial progressive industry trends in the Europe human liver models market, thereby allowing players across the value chain to develop effective long-term strategies - Develop/modify business expansion plans by using substantial growth offering developed and emerging markets - Scrutinize in-depth Europe market trends and outlook coupled with the factors driving the human liver models market, as well as those hindering it - Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to client products, segmentation, pricing, and distribution

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