The US, Canada, and Mexico are major economies in North America. Biopsies are performed on small samples of tissues extracted from a mass or tumor; they involve microscopic studies to determine the cause of a bulge or tumor. Biopsies are generally used to diagnose cancer cells, infections, and other disorders. The frozen section is a type of biopsy treatment that was created to make a quick identification of a mass during surgery. The procedure is known as cryosection, and it is performed using an instrument named cryostat. This procedure is mainly performed during oncology-related surgeries. Frozen tissue samples are helpful in the identification of lesions or tumors as they allow a surgeon to see if a sample has malignant or benign components and if the tumor has metastasized. The surgeon can then decide whether there is a compelling reason to continue the surgery. Determining the organ of origin using frozen tissue samples is important when dealing with tissue such as parathyroid glands that are too small and difficult to recognize. Moreover, frozen tissue samples are utilized to determine whether the tumor has spread to the lymph nodes and nerves. It is also sometimes used to check for distant organ metastasis. Frozen tissue samples are preferred in analyses such as mass spectrometry, next-generation sequencing, western blotting-based post-translational protein modification determination, and quantitative real-time polymerase chain reaction. In addition, when the strands are longer than 50 pairs, frozen tissue samples are the gold standard for DNA and RNA sequencing. Frozen tissue samples are also beneficial in immunohistochemistry as the proteins are still in their native states.
Several research studies are conducted using frozen tissue samples in various therapeutic areas, such as oncology, inflammation, and neurological diseases/central nervous system (CNS). For instance, rheumatoid arthritis (RA), a chronic autoimmune disorder causing joint inflammation and damage, is one of the most studied indications in recent years. Like many rheumatic diseases, RA affects the synovial tissue. The synovial tissue biopsy provides a better understanding of disease pathophysiology, and facilitates the discovery of new biomarkers for diagnosis, prognosis, and identification of new therapeutic targets. Synovial tissue examination by frozen section provides detailed information regarding diagnosis and treatment of the disease. Frozen tissue samples have been used widely in medical research on cancer and other disorders to examine cell morphology, disease state, intra and intercellular communication, and biopsied tissue sections. As most biological materials are fragile and perishable, special precautions are taken while handling and preserving frozen tissue samples.
With new features and technologies, vendors can attract new customers and expand their footprints in emerging markets. This factor is likely to drive the North America frozen tissues samples market at a notable CAGR during the forecast period.
The North America frozen tissues samples market is segmented on the basis of product type, application, end user, and country. The market, based on product, is segmented into frozen normal tissues samples, frozen tumor tissues samples, and frozen diseased tissue samples. The frozen tissue tumor samples segment held the largest share of the market in 2021. Based on application, the North America frozen tissues samples market is segmented into disease diagnosis and treatment, cancer and other diseases research, and morphological analysis. In 2021, the cancer and other diseases research segment accounted for the largest share of the market. The North America frozen tissues samples market, by end user, is segmented into academic and research institutes, hospitals and clinics, diagnostic centers, and others. In 2021, the academic and research institutes segment held the largest market share. Based on country, the North America frozen tissues samples market is segmented into the US, Canada, and Mexico. The US held the largest market share in 2021.
AMS Biotechnology Ltd.; Audubon Bioscience Co; Bay Biosciences LLC; BioChain Institute Inc.; Geneticist, Inc.; OriGene Technologies, Inc.; ProteoGenex, Inc.; REPROCELL Inc.; US Biolab Corporation, Inc.; and ZenBio, Inc. are among the leading companies in the North America frozen tissues samples market.