Asia Pacific Human Liver Models Market Forecast to 2028 - COVID-19 Impact and Regional Analysis By Type (Liver Organoids, Liver-on-a-chip, 2D Models, 3D Bioprinting, and Others), Application (Drug Discovery, Educational, and Others), and End User (Pharmaceutical and Biotechnology Companies, Research Institutes, and Others)

TIPRE00026111 | Pages: 112 | Biotechnology | Nov 2021 | Type: Regional | Status: Published
The APAC human liver models market is expected to grow from US$ 33,191.56 thousand in 2021 to US$ 76,341.40 thousand by 2028; it is estimated to grow at a CAGR of 12.6% from 2021 to 2028.

China, Japan, India, South Korea, and Australia are major economies in APAC. Increasing focus on drug discovery activities is expected to surge the market growth. Before a new drug is tested in a clinical study, the main phase analysis of pharmacodynamics and pharmacokinetics is carried out using animal models and two-dimensional (2D) in vitro models. The It takes 1215 years and US$ 35 billion to bring a single drug to market. The increasing demand for new and advanced drugs is driving the general pace of drug discovery and discovery. As a result, a high number of clinical studies are being conducted to invent and commercialize new drugs. Even after the market launch (phase IV), there are still many drug withdrawals for toxicological reasons. About 1830% of these withdrawals are due to hepatotoxic effects, which shows that the liver is the most common target for adverse drug reactions (ADRs). The liver plays a crucial role in drug metabolism, body homeostasis, digestion, and toxic substance excretion. In the case of the liver, the simplest models for drug discovery are isolated subcellular fractions, such as microsomes, which contain drug-metabolizing enzymes (DMEs) or isolated mitochondria. To enable high sensitivity and specificity, the cell-based models are required to replicate higher order drug processes [i.e., biotransformation, transport kinetics, secondary metabolite formation, and drug interactions (DDIs)]. Human liver models are used to assess the metabolism and toxicity of chemical compounds and drugs, and to assess drug candidates in cancer research and genetic studies. The significant increase in clinical trials is expected to fuel demand for advanced medical technologies, including organoid models, thereby driving the APAC market growth.

The APAC biopharmaceutical industry has been disturbed for a few months in 2020 during the outbreak of COVID-19. The COVID-19 pandemic interrupted clinical trials due to restrictions imposed to control the spread of infection. However, with the rising demand for products to treat the COVID-19 infection, the biopharmaceutical and pharmaceutical companies in India and China continued to focus on research activities. For instance, in February 2020, Vir Biotechnology (US) partnered with WuXi Biologics (China) to develop human monoclonal antibodies to treat COVID-19 infections. This partnership involves clinical development, manufacturing, and commercialization, and WuXi Biologics will be responsible for process and formulation development and early production for clinical development. Moreover, companies in the region have put core activities on hold to focus on the COVID-19 vaccine development. For instance, in March 2020, biotech CRO Novotech (Australia) partnered with Komipharm International (South Korea) for clinical trials of Panaphix as a potential treatment for COVID-19. The recent restrictions imposed by many countries in response to the COVID-19 outbreak have impacted ongoing clinical research.

With the new features and technologies, vendors can attract new customers and expand their footprints in emerging markets. This factor is likely to drive the APAC human liver models market. The APAC human liver models market is expected to grow at a good CAGR during the forecast period.

APAC Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousand)

APAC Human Liver Models Market Segmentation
APAC Human Liver Models Market By Type
- Liver Organoids
- Liver-on-a-chip
- 2D Models
- 3D Bioprinting
- Others
APAC Human Liver Models Market By Application
- Drug Discovery
- Educational
- Others
APAC Human Liver Models Market By End User
- Pharmaceutical and Biotechnology Companies
- Research Institutes
- Others
APAC Human Liver Models Market, by Country
- Japan
- China
- India
- South Korea
- Australia
- Rest of APAC
APAC Human Liver Models Market -Companies Mentioned
- BioIVT
- CELLINK
- CYFUSE BIOMEDICAL K.K.
- Emulate, Inc.
- InSphero
- Kerafast
- MIMETAS BV
- THERMO FISHER SCIENTIFIC INC.

TABLE OF CONTENTS
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 APAC Human Liver Models Market By Type
1.3.2 APAC Human Liver Models Market By Application
1.3.3 APAC Human Liver Models Market By End User
1.3.4 APAC Human Liver Models Market By Country
2. Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. APAC Human Liver Models Market Market Landscape
4.1 Overview
4.2 APAC PEST Analysis
4.3 Experts Opinion
5. APAC Human Liver Models Market Key Market Dynamics
5.1 Market Drivers
5.1.1 Increasing Prevalence of Liver Diseases
5.1.2 Growing Focus on Developing Alternatives for Animal Testing Models
5.2 Market Restraints
5.2.1 High Costs of Liver Models
5.3 Market Opportunities
5.3.1 Increasing focus on Drug Discovery Activities
5.4 Future Trends
5.4.1 Technology Advancements in Organ Printing
5.1 Impact analysis
6. Human Liver Models Market APAC Analysis
6.1 APAC Human Liver Models Market Revenue Forecast and Analysis
7. APAC Human Liver Models Market Analysis By Type
7.1 Overview
7.2 APAC Human Liver Models Market Revenue Share, by Type (2021 and 2028)
7.3 Liver Organoids
7.3.1 Overview
7.3.2 Liver Organoids: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.4 Liver-on-a-chip
7.4.1 Overview
7.4.2 Liver-on-a-chip: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.5 2D Models
7.5.1 Overview
7.5.2 2D Models: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.6 3D Bioprinting
7.6.1 Overview
7.6.2 3D Bioprinting: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
7.7 Others
7.7.1 Overview
7.7.2 Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
8. APAC Human Liver Models Market Analysis By Application
8.1 Overview
8.2 APAC Human Liver Models Market Share, by Application, 2021 and 2028, (%)
8.3 Educational
8.3.1 Overview
8.3.2 Educational: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
8.4 Drug Discovery
8.4.1 Overview
8.4.2 Drug Discovery: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
8.5 Other
8.5.1 Overview
8.5.2 Other: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
9. APAC Human Liver Models Market Analysis By End User
9.1 Overview
9.2 APAC Human Liver Models Market Share, by End User, 2021 and 2028, (%)
9.3 Research Institutes
9.3.1 Overview
9.3.2 Research Institutes: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
9.4 Pharmaceutical and Biotechnology Companies
9.4.1 Overview
9.4.2 Pharmaceutical and Biotechnology Companies: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
9.5 Others
9.5.1 Overview
9.5.2 Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
10. APAC Human Liver Models Market Country Analysis
10.1 APAC: Human Liver Models Market
10.1.1 Overview
10.1.2 APAC: Human Liver Models Market, by Country, 2021 & 2028 (%)
10.1.2.1 China: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.1.1 China: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.1.2 China: Human Liver Models Market, by Type, 20192028 (USD Thousand)
10.1.2.1.3 China: Human Liver Models Market, By Application, 20192028 (USD Thousand)
10.1.2.1.4 China: Human Liver Models Market, by End User, 20192028 (USD Thousand)
10.1.2.2 Japan: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.2.1 Japan: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.2.2 Japan: Human Liver Models Market, by Type, 20192028 (USD Thousand)
10.1.2.2.3 Japan: Human Liver Models Market, By Application, 20192028 (USD Thousand)
10.1.2.2.4 Japan: Human Liver Models Market, by End User, 20192028 (USD Thousand)
10.1.2.3 India: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.3.1 India: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.3.2 India: Human Liver Models Market, by Type, 20192028 (USD Thousand)
10.1.2.3.3 India: Human Liver Models Market, By Application, 20192028 (USD Thousand)
10.1.2.3.4 India: Human Liver Models Market, by End User, 20192028 (USD Thousand)
10.1.2.4 Australia: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.4.1 Australia: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.4.2 Australia: Human Liver Models Market, by Type, 20192028 (USD Thousand)
10.1.2.4.3 Australia: Human Liver Models Market, By Application, 20192028 (USD Thousand)
10.1.2.4.4 Australia: Human Liver Models Market, by End User, 20192028 (USD Thousand)
10.1.2.5 South Korea: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.5.1 South Korea: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.5.2 South Korea: Human Liver Models Market, by Type, 20192028 (USD Thousand)
10.1.2.5.3 South Korea: Human Liver Models Market, By Application, 20192028 (USD Thousand)
10.1.2.5.4 South Korea: Human Liver Models Market, by End User, 20192028 (USD Thousand)
10.1.2.6 Rest of APAC: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.6.1 Rest of APAC: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
10.1.2.6.2 Rest of APAC: Human Liver Models Market, by Type, 20192028 (USD Thousand)
10.1.2.6.3 Rest of APAC: Human Liver Models Market, By Application, 20192028 (USD Thousand)
10.1.2.6.4 Rest of APAC: Human Liver Models Market, by End User, 20192028 (USD Thousand)
11. Impact Of COVID-19 Pandemic on APAC Human Liver Models Market
11.1 APAC: Impact Assessment of COVID-19 Pandemic
12. Industry Landscape
12.1 Overview
12.2 Organic Developments
12.2.1 Overview
12.3 Inorganic Developments
12.3.1 Overview
13. Company Profiles
13.1 THERMO FISHER SCIENTIFIC INC.
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
13.2 Emulate, Inc.
13.2.1 Key Facts
13.2.2 Business Description
13.2.3 Products and Services
13.2.4 Financial Overview
13.2.5 SWOT Analysis
13.2.6 Key Developments
13.3 CYFUSE BIOMEDICAL K.K.
13.3.1 Key Facts
13.3.2 Business Description
13.3.3 Products and Services
13.3.4 Financial Overview
13.3.5 SWOT Analysis
13.3.6 Key Developments
13.4 MIMETAS BV
13.4.1 Key Facts
13.4.2 Business Description
13.4.3 Products and Services
13.4.4 Financial Overview
13.4.5 SWOT Analysis
13.4.6 Key Developments
13.5 InSphero
13.5.1 Key Facts
13.5.2 Business Description
13.5.3 Products and Services
13.5.4 Financial Overview
13.5.5 SWOT Analysis
13.5.6 Key Developments
13.6 BioIVT
13.6.1 Key Facts
13.6.2 Business Description
13.6.3 Products and Services
13.6.4 Financial Overview
13.6.5 SWOT Analysis
13.6.6 Key Developments
13.7 CELLINK
13.7.1 Key Facts
13.7.2 Business Description
13.7.3 Products and Services
13.7.4 Financial Overview
13.7.5 SWOT Analysis
13.7.6 Key Developments
13.8 Kerafast
13.8.1 Key Facts
13.8.2 Business Description
13.8.3 Products and Services
13.8.4 Financial Overview
13.8.5 SWOT Analysis
13.8.6 Key Developments
14. Appendix
14.1 About The Insight Partners
14.2 Glossary of Terms


LIST OF TABLES
Table 1. APAC Human Liver Models Market, Revenue and Forecast, 20192028 (US$ Thousand)
Table 2. China: Human Liver Models Market, by Type Revenue and Forecast to 2028 (USD Thousand)
Table 3. China: Human Liver Models Market, By Application Revenue and Forecast to 2028 (USD Thousand)
Table 4. China: Human Liver Models Market, by End User Revenue and Forecast to 2028 (USD Thousand)
Table 5. Japan: Human Liver Models Market, by Type Revenue and Forecast to 2028 (USD Thousand)
Table 6. Japan: Human Liver Models Market, By Application Revenue and Forecast to 2028 (USD Thousand)
Table 7. Japan: Human Liver Models Market, by End User Revenue and Forecast to 2028 (USD Thousand)
Table 8. India: Human Liver Models Market, by Type Revenue and Forecast to 2028 (USD Thousand)
Table 9. India: Human Liver Models Market, By Application Revenue and Forecast to 2028 (USD Thousand)
Table 10. India: Human Liver Models Market, by End User Revenue and Forecast to 2028 (USD Thousand)
Table 11. Australia: Human Liver Models Market, by Type Revenue and Forecast to 2028 (USD Thousand)
Table 12. Australia: Human Liver Models Market, By Application Revenue and Forecast to 2028 (USD Thousand)
Table 13. Australia: Human Liver Models Market, by End User Revenue and Forecast to 2028 (USD Thousand)
Table 14. South Korea: Human Liver Models Market, by Type Revenue and Forecast to 2028 (USD Thousand)
Table 15. South Korea: Human Liver Models Market, By Application Revenue and Forecast to 2028 (USD Thousand)
Table 16. South Korea: Human Liver Models Market, by End User Revenue and Forecast to 2028 (USD Thousand)
Table 17. Rest of APAC: Human Liver Models Market, by Type Revenue and Forecast to 2028 (USD Thousand)
Table 18. Rest of APAC: Human Liver Models Market, By Application Revenue and Forecast to 2028 (USD Thousand)
Table 19. Rest of APAC: Human Liver Models Market, by End User Revenue and Forecast to 2028 (USD Thousand)
Table 20. Organic Developments Done by Companies
Table 21. Inorganic Developments Done by Companies
Table 22. Glossary of Terms


LIST OF FIGURES
Figure 1. APAC Human Liver Models Market Segmentation
Figure 2. APAC Human Liver Models Market Segmentation, By Country
Figure 3. APAC Human Liver Models Market Overview
Figure 4. Liver Organoids Held the Largest Share in 2020
Figure 5. India to Show Significant Growth During Forecast Period
Figure 6. APAC PEST Analysis
Figure 7. APAC Human Liver Models Market Impact Analysis of Drivers and Restraints
Figure 8. APAC Human Liver Models Market Revenue Forecast and Analysis
Figure 9. APAC Human Liver Models Market Revenue Share, by Type (2021 and 2028)
Figure 10. APAC Liver Organoids: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 11. APAC Liver-on-a-chip: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 12. APAC 2D Models: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 13. APAC 3D Bioprinting: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 14. APAC Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 15. APAC Human Liver Models Market Share, by Application, 2021 and 2028 (%)
Figure 16. APAC Educational: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 17. APAC Drug Discovery: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 18. APAC Other: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 19. APAC Human Liver Models Market Share, by End User, 2021 and 2028 (%)
Figure 20. APAC Research Institutes: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 21. APAC Pharmaceutical and Biotechnology Companies: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 22. APAC Others: Human Liver Models Market Revenue and Forecast to 2028 (US$ Thousands)
Figure 23. APAC: Human Liver Models Market, by Key Country Revenue (2021) (USD Thousand)
Figure 24. APAC: Human Liver Models Market, by Country, 2021 & 2028 (%)
Figure 25. China: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
Figure 26. Japan: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
Figure 27. India: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
Figure 28. Australia: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
Figure 29. South Korea: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
Figure 30. Rest of APAC: Human Liver Models Market Revenue and Forecast to 2028 (USD Thousand)
Figure 31. Impact of COVID-19 Pandemic in APAC Country Markets

1. BioIVT
2. CELLINK
3. CYFUSE BIOMEDICAL K.K.
4. Emulate, Inc.
5. InSphero
6. Kerafast
7. MIMETAS BV
8. THERMO FISHER SCIENTIFIC INC.

- Save and reduce time carrying out entry-level research by identifying the growth, size, leading players, and segments in the APAC human liver models market. - Highlights key business priorities in order to assist companies to realign their business strategies - The key findings and recommendations highlight crucial progressive industry trends in the APAC human liver models market, thereby allowing players across the value chain to develop effective long-term strategies - Develop/modify business expansion plans by using substantial growth offering developed and emerging markets - Scrutinize in-depth APAC market trends and outlook coupled with the factors driving the human liver models market, as well as those hindering it - Enhance the decision-making process by understanding the strategies that underpin commercial interest with respect to client products, segmentation, pricing, and distribution
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